Soft materials based on designed self-assembling peptides: from design to application

被引:29
作者
Tsutsumi, Hiroshi [1 ]
Mihara, Hisakazu [1 ]
机构
[1] Tokyo Inst Technol, Grad Sch Biosci & Biotechnol, Dept Bioengn, Midori Ku, Yokohama, Kanagawa 2268501, Japan
关键词
DE-NOVO DESIGN; HYDROPHOBIC ANTICANCER DRUG; SURFACTANT-LIKE PEPTIDES; BETA-SHEET; AMPHIPHILE NANOFIBERS; CARBON NANOTUBES; RATIONAL DESIGN; COMPLEMENTARY OLIGOPEPTIDE; CONTROLLED-RELEASE; PROGENITOR CELLS;
D O I
10.1039/c3mb25442a
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Self-assembling peptides (SAPs) are one of the useful tools to fabricate various nanostructures and resulting higher macrostructures from them based on supramolecular chemistry. Recent continuous studies on SAPs give us much important knowledge, from the design of SAPs to their application as nanomaterials and biomaterials. The process from design to application of SAPs includes steps of optimization in self-assembling properties and functionalization. This review briefly describes general designs of SAPs, control and functionalization methods of nanostructures fabricated from SAPs and recent application examples.
引用
收藏
页码:609 / 617
页数:9
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