Cellular stress and signal transduction responses to human cytomegalovirus infection

被引：30
|
作者：
Evers, DL
Wang, X
Huang, ES
机构：
[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA
[3] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA
[4] Univ N Carolina, Curriculum Genet & Mol Biol, Chapel Hill, NC 27599 USA
来源：
MICROBES AND INFECTION | 2004年 / 6卷 / 12期
关键词：
cytomegalovirus; signal transduction; cytokine; antiviral;
D O I：
10.1016/j.micinf.2004.05.026
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human cytomegalovirus (HCMV) receptor-ligand interactions and viral entry excite cellular responses such as receptor tyrosine kinase and mitogen-activated protein kinase signaling, cytoskeletal rearrangement, and the induction of transcription factors, prostaglandins, and cytokines. Bi-phasic stimulation of these pathways, excepting interferon, facilitates productive viral infection and likely contributes to viral pathogenesis. (c) 2004 Elsevier SAS. All rights reserved.
引用
收藏
页码：1084 / 1093
页数：10
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