Enantioseparations of chiral ruthenium(II) polypyridyl complexes using HPLC with macrocyclic glycopeptide chiral stationary phases (CSPs)

被引：15
作者：
Sun, Ping [1 ]
Krishnan, Arthi [1 ]
Yadav, Abhishek [1 ]
MacDonnell, Frederick M. [1 ]
Armstrong, Daniel W. [1 ]
机构：
[1] Univ Texas Arlington, Dept Chem & Biochem, Arlington, TX 76019 USA
来源：
JOURNAL OF MOLECULAR STRUCTURE | 2008年 / 890卷 / 1-3期
关键词：
Chiral stationary phase; HPLC; Macrocyclic glycopeptide; Enantioresolution;
D O I：
10.1016/j.molstruc.2008.02.030
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A high-performance liquid chromatographic method using macrocyclic glycopeptide chiral stationary phases (CSPs) was used to separate enantiomers of seven ruthenium(II) polypyridyl complexes. Among the five different CSPs, the Chirobiotic T2 was most effective and baseline separated all complexes. All complexes show the same elution order with the Delta-enantiomer being retained longer than the Delta-enantiomer. The mobile phase composition, including organic modifier type, organic modifier percent. salt type, and salt concentration, produced significant effects on the enantioresolution. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：75 / 80
页数：6
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