Percutaneous Patent Foramen Ovale Closure After Stroke

被引：4

作者：

Lee, Oh-Hyun ^{[1
,2
]}

Kim, Jung-Sun ^{[3
,4
]}

机构：

[1] Yonsei Univ, Coll Med, Dept Internal Med, Div Cardiol, Yongin, South Korea

[2] Yongin Severance Hosp, Cardiovasc Ctr, Yongin, South Korea

[3] Yonsei Univ, Coll Med, Severance Cardiovasc Hosp, Div Cardiol, Seoul, South Korea

[4] Yonsei Univ, Coll Med, Severance Cardiovasc Hosp, Div Cardiol, 50-1 Yonsei Ro, Seoul 03722, South Korea

来源：

KOREAN CIRCULATION JOURNAL | 2022年 / 52卷 / 11期

关键词：

Patent foramen ovale; Stroke; Paradoxical embolism; MEDICAL THERAPY; DEVICE CLOSURE; CRYPTOGENIC STROKE;

D O I：

10.4070/kcj.2022.0258

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Percutaneous patent foramen ovale (PFO) closure in patients with a prior PFO-associated stroke showed a risk reduction of the stroke recurrence compared to the medical therapy alone in recent several studies. Nevertheless, optimal patient selection for PFO closure has not been clarified. In this paper, we discuss the characteristics of PFO-associated strokes and discuss the recently published evidence and patient selection for PFO closure in patients with ischemic stroke. The lesions characteristics of PFO-associated stroke are associated with multiple scattered lesion, small sized cerebral cortical lesion, or posterior circulation. Overcoming the failure of early studies in CLOSURE I, PC, and RESPECT trials, PFO closure showed a significant reduction in recurrent stroke in recently published REDUCE, CLOSE, DEFENSE -PRO trials, and long-term follow-up data of RESPECT study. However, considering that PFO closure cannot completely prevent stroke recurrence and that complications including atrial fibrillation, we should be selectively performed in patients with high-risk PFO.

引用

页码：801 / 807

页数：7

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