Nickel-catalyzed C-P cross-coupling of diphenylphosphine oxide with aryl chlorides

被引：91

作者：

Zhang, Hong-Yu ^{[1
]}

Sun, Meng ^{[1
]}

Ma, Yan-Na ^{[1
]}

Tian, Qiu-Ping ^{[1
]}

Yang, Shang-Dong ^{[1
,2
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 48期

基金：

高等学校博士学科点专项科研基金;

关键词：

LIGANDS; PHOSPHINES; HALIDES;

D O I：

10.1039/c2ob26874d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel protocol for the preparation of various diarylphosphine oxide compounds via a Ni-catalyzed cross-coupling of aryl chlorides with R2P(O)H has been developed. Notably, this process exhibits the following very attractive features: (i) the process is simpler and operates under mild reaction conditions; (ii) the process is generally cheaper in part because the more accessible aryl chloride is used to form the C-P bond; (iii) the process avoids the need for simultaneous preparation and use of Ar2P(O)M.

引用

页码：9627 / 9633

页数：7

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