In this paper, the RBF neural network case teaching has been studied. In the actual teaching process, we find it more difficult for student to learn the course, duing to the RBF neural network curriculum theory is more stronger. Many students do not know how to use the theory to solve practical problems. Therefore, we equip students with basic knowledge of RBF neural network through case teaching. In this paper, a RBF neural network example has been analysised and applied to enable the students to learn RBF neural network. Teaching practice shows that case teaching can achieve better teaching effectiveness.