Is Early Intervention for Psychosis Feasible and Effective?

被引:48
作者
Srihari, Vinod H. [1 ,2 ]
Shah, Jai [3 ]
Keshavan, Matcheri S. [4 ,5 ]
机构
[1] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA
[2] Connecticut Mental Hlth Ctr, Clin Specialized Treatment Early Psychosis STEP, New Haven, CT 06519 USA
[3] Harvard Univ, Sch Med, Dept Psychiat, Harvard Longwood Psychiat Residency Training Prog, Boston, MA 02215 USA
[4] Harvard Univ, Sch Med, Dept Psychiat, Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[5] Harvard Univ, Sch Med, Massachusetts Mental Hlth Ctr, Boston, MA 02215 USA
关键词
Psychosis; Schizophrenia; Early intervention; Critical period; 5-YEAR FOLLOW-UP; COGNITIVE ENHANCEMENT THERAPY; RANDOMIZED MULTICENTER TRIAL; GRAY-MATTER LOSS; UNTREATED PSYCHOSIS; COST-EFFECTIVENESS; 1ST-EPISODE SCHIZOPHRENIA; 1ST EPISODE; STANDARD TREATMENT; EXPRESSED EMOTION;
D O I
10.1016/j.psc.2012.06.004
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Services that provide comprehensive, early intervention (El) have shown promise in improving long-term outcomes in schizophrenia. This article reviews the rationale and salient concepts relevant to understanding the growing El literature. A selective review of studies evaluating the effectiveness of integrated El is followed by a discussion of feasibility, especially in the US context. Finally, the authors present a framework that seeks to integrate activities traditionally categorized and separated as discovery and implementation. This framework is offered as a way to advance both goals.
引用
收藏
页码:613 / +
页数:20
相关论文
共 101 条
[1]   Cost-effectiveness of treating first-episode psychosis: five-year follow-up results from an Italian early intervention programme [J].
Angelo, Cocchi ;
Vittorio, Mapelli ;
Anna, Meneghelli ;
Antonio, Preti .
EARLY INTERVENTION IN PSYCHIATRY, 2011, 5 (03) :203-211
[2]  
[Anonymous], IMPLEMENTING EARLY I
[3]   Cognitive reserve in neuropsychiatry [J].
Barnett, J. H. ;
Salmond, C. H. ;
Jones, P. B. ;
Sahakian, B. J. .
PSYCHOLOGICAL MEDICINE, 2006, 36 (08) :1053-1064
[4]   Economic evaluations in evidence based healthcare [J].
Barrett, Barbara ;
Byford, Sarah .
EVIDENCE-BASED MENTAL HEALTH, 2009, 12 (02) :36-39
[5]  
Bero LA, 1998, BMJ-BRIT MED J, V317, P465
[6]   Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness [J].
Bertelsen, Mette ;
Jeppesen, Pia ;
Petersen, Lone ;
Thorup, Anne ;
Ohlenschlaeger, Johan ;
le Quach, Phuong ;
Christensen, Torben Ostergaard ;
Krarup, Gertrud ;
Jorgensen, Per ;
Nordentoft, Merete .
ARCHIVES OF GENERAL PSYCHIATRY, 2008, 65 (07) :762-771
[7]   Early intervention in psychosis - The critical period hypothesis [J].
Birchwood, M ;
Todd, P ;
Jackson, C .
BRITISH JOURNAL OF PSYCHIATRY, 1998, 172 :53-59
[8]  
Bleuler M., 1978, The schizophrenic disorders: Long-term patient and family studies
[9]   Review of the operational definition for first-episode psychosis [J].
Breitborde, Nicholas J. K. ;
Srihari, Vinod H. ;
Woods, Scott W. .
EARLY INTERVENTION IN PSYCHIATRY, 2009, 3 (04) :259-265
[10]   INFLUENCE OF FAMILY LIFE ON COURSE OF SCHIZOPHRENIC DISORDERS - REPLICATION [J].
BROWN, GW ;
BIRLEY, JLT ;
WING, JK .
BRITISH JOURNAL OF PSYCHIATRY, 1972, 121 (562) :241-+