Synthesis of Diazo Compounds by Using NaN3 and Inexpensive SO2F2

被引：2

作者：

Ye, Cuijiao ^{[1
]}

Yan, Zhaohua ^{[1
]}

Chen, Guanghui ^{[1
]}

Xie, Hongyan ^{[1
]}

Zhang, Minxiang ^{[1
]}

Lin, Sen ^{[1
]}

机构：

[1] Nanchang Univ, Sch Chem & Chem Engn, 999 Xuefu Dadao, Nanchang 330031, Jiangxi, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 2022卷 / 43期

基金：

中国国家自然科学基金;

关键词：

Active methylene compounds; Diazo compounds; Diazotization; Sulfuryl fluoride; Synthetic methods; IMIDAZOLE-1-SULFONYL AZIDE; C-H; DIAZOTRANSFER; EFFICIENT; REAGENT; ALKYNES; YLIDES; SAFE;

D O I：

10.1002/ejoc.202200584

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise and efficient method was developed in which sodium azide (NaN3) and sulfuryl fluoride (SO2F2) were directly employed to synthesize diazo compounds with active methylene compounds. A variety of diazo compounds were produced in good to excellent yields. This protocol avoids the use of organosulfonyl azides, and features atom economy and mild reaction conditions. An alternate method for the synthesis of diazo compounds was provided.

引用

页数：4

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