Terahertz spectroscopy of breast tumors

被引：0

作者：

Ashworth, Philip C. ^{[1
,2
]}

Pickwell-MacPherson, Emma ^{[3
]}

Pinder, Sarah E. ^{[4
]}

Provenzano, Elena ^{[4
]}

Purushotham, Anand D. ^{[5
]}

Pepper, Michael ^{[1
,6
]}

Wallace, Vincent P. ^{[2
]}

机构：

[1] Univ Cambridge, Cavendish Lab, JJ Thompson Ave, Cambridge CB3 0HE, England

[2] Tera View Ltd, Cambridge CB40WS, England

[3] Chinese Univ Hong Kong, Hong Kong, Peoples R China

[4] NHS Fdn, Dept Histopathol, Cambridge CB2 2QQ, England

[5] Guys Hosp, London, England

[6] Univ Cambridge, Cavendish Lab, Cambridge CB3 0HE, England

来源：

2007 JOINT 32ND INTERNATIONAL CONFERENCE ON INFRARED AND MILLIMETER WAVES AND 15TH INTERNATIONAL CONFERENCE ON TERAHERTZ ELECTRONICS, VOLS 1 AND 2 | 2007年

基金：

英国工程与自然科学研究理事会;

关键词：

biomedical imaging; pulse analysis; THz spectroscopy; tumors;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Using a portable terahertz pulsed spectrometer developed by TeraView Ltd. the complex refractive indices of ex vivo breast tumors were measured through transmission in the range of 0.1 - 3 THz. Twenty samples were measured at room temperature and it is shown here that the use of terahertz pulsed spectroscopy (TPS) enables us to distinguish between normal adipose tissue, normal fibrous tissue and breast tumors due to the higher water content and structural differences found in tumors. Comparisons are made between the results found using TPS and the classification of the tissue samples given through histology performed at Addenbrooke's Hospital, Cambridge. Further measurements have been taken at low temperatures (down to 200K) to remove the dominant absorption caused by water in an attempt to identify other differences, such as the cell and protein density, between normal breast tissue and tumors observable in the THz range.

引用

页码：590 / +

页数：2

共 6 条

[1]

[Anonymous], CANC FACTS FIG 2007

[2]

Ashworth PC, 2006, CONFERENCE DIGEST OF THE 2006 JOINT 31ST INTERNATIONAL CONFERENCE ON INFRARED AND MILLIMETER WAVES AND 14TH INTERNATIONAL CONFERENCE ON TERAHERTZ ELECTRONICS, P184

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[4]

Nass S.J., 2001, Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer

[5]

PICKWELL E, 2005, THESIS CAMBRIDGE U

[6] Optical constants of ice Ih crystal at terahertz frequencies [J].

Zhang, C ;

Lee, KS ;

Zhang, XC ;

Wei, X ;

Shen, YR .

APPLIED PHYSICS LETTERS, 2001, 79 (04) :491-493

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