Neurodegeneration: RNA turns number one suspect in polyglutamine diseases

被引：4
|
作者：
Birman, Serge [1 ]
机构：
[1] Univ Mediterranee, CNRS, UMR 6216, Dev Biol Inst Marseille, F-13288 Marseille 9, France
来源：
CURRENT BIOLOGY | 2008年 / 18卷 / 15期
关键词：
D O I：
10.1016/j.cub.2008.06.023
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Polyglutamine expansion diseases are triggered by the accumulation of toxic proteins. A new study reports that RNA molecules containing long CAG repeats can also be toxic to neurons and may play a significant role in pathogenesis.
引用
收藏
页码：R659 / R661
页数：3
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