Functional cellulose-based hydrogels as extracellular matrices for tissue engineering

被引：137

作者：

Dutta, Sayan Deb ^{[1
]}

Patel, Dinesh K. ^{[2
]}

Lim, Ki-Taek ^{[1
]}

机构：

[1] Kangwon Natl Univ, Biorobot Lab, Dept Biosyst Engn, Chunchon, South Korea

[2] Kangwon Natl Univ, Inst Forest Sci, Chunchon 24341, South Korea

来源：

JOURNAL OF BIOLOGICAL ENGINEERING | 2019年 / 13卷 / 1期

基金：

新加坡国家研究基金会;

关键词：

Cellulose; Hydrogels; Scaffolds; Extracellular matrices; Tissue engineering; BACTERIAL-CELLULOSE; POLY(ETHYLENE GLYCOL); MICROBIAL CELLULOSE; DRUG-DELIVERY; CROSS-LINKING; IN-VITRO; PACKING ANALYSIS; HYALURONIC-ACID; IONIC LIQUID; MEMBRANES;

D O I：

10.1186/s13036-019-0177-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Cellulose-based hydrogels are immensely important for tissue engineering. In this review, we attempt to document the source, nature, and application of cellulose-based hydrogels as an extracellular matrix for tissue growth and regeneration. Hydrogels can be prepared either from native cellulose, including both bacterial and plant sources or from cellulose derivatives, such as methyl cellulose, carboxymethylcellulose, and hydroxypropylmethylcellulose or even metal ions such as silver. Cellulose-polymer composite (polymers that include natural sources including chitosan, starch, alginates, collagen, hyaluronic acid, and chitin) are an attractive, inexpensive, and advantageous structural material that is easy to use. Cellulose-based scaffolding materials are widely used in the regeneration of various tissues, such as bone, cartilage, heart, blood vessel, nerve, and liver, among others. In this review, we discuss the most important applications of cellulosic hydrogels in tissue engineering based on their structural compositions.

引用

页数：19

共 218 条

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