Prevalence of human respiratory syncytial virus in Iran: a systematic review and meta-analysis

Aim: We sought to determine the prevalence of human respiratory syncytial virus (HRSV) in people in Iran between the year 1996 and 2016. Methods: Prevalence of HRSV in Iran was determined from 1996 to 2016 using data from PubMed, Web of Science, EMBASE, Cochrane Library, Google Scholar and Iranian databases. Analysis was performed by Comprehensive Meta-Analysis software. Result: The prevalence of HRSV infections was 18.0% (95% CI: 14.6-22.0) in people in different regions of Iran. Additionally, the incidence of HRSV in north, center, west and south of Iran were 16.4% (95% CI: 11.8-22.4), 20.0% (95% CI: 15.5-25.5), 16.8% (95% CI: 10.0-27.0) and 10.6% (95% CI: 2.4-36.9), respectively. Conclusion: According to the high prevalence of HRSV infection among people with respiratory infections in Iran, HRSV screening and evaluating of co-circulate HRSV genotypes can be helpful for vaccination design in the future.