A study of the insertion-deletion polymorphism of the serotonin transporter gene in populations from the Volga-Ural region

被引:0
作者
Gorbunova, EV [1 ]
Galeyeva, AR [1 ]
Khusnutdinova, EK [1 ]
机构
[1] Russian Acad Sci, Ufa Res Ctr, Dept Biochem & Genet, Ufa 450054, Russia
基金
俄罗斯基础研究基金会;
关键词
Polymerase Chain Reaction; Serotonin; Transporter Gene; Population Parameter; Serotonin Transporter;
D O I
10.1023/A:1015222907935
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The insertion-deletion polymorphism of the serotonin transporter gene (SLC6A4) was studied using the polymerase chain reaction (PCR) in eight populations from the Volga-Ural region (the Bashkir, Chuvash, Tatar, Udmurt, Mari, Mordovian, and Komi populations and the population of Russians living in the Arkhangel'skii raion of Bashkortostan). For this polymorphic system, the pattern of distribution of main population parameters was established in the region studied. Depending on population ethnicity, specific trends were revealed in the pattern of frequencies of alleles and genotypes of gene SLC6A4.
引用
收藏
页码:470 / 472
页数:3
相关论文
共 7 条
[1]   Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism [J].
Flory, JD ;
Manuck, SB ;
Ferrell, RE ;
Dent, KM ;
Peters, DG ;
Muldoon, MF .
MOLECULAR PSYCHIATRY, 1999, 4 (01) :93-96
[2]  
HELIAS A, 1999, J NEUROCHEM, V66, P2621
[3]  
Ishiguro H, 1999, ALCOHOL CLIN EXP RES, V23, P1281
[4]  
POPOVA NK, 2000, SVOREMENNYE KONTSEPT, P319
[5]   Schizophrenia and the serotonin transporter gene [J].
Rao, D ;
Jönsson, EG ;
Paus, S ;
Ganguli, R ;
Nöthen, M ;
Nimgaonkar, VL .
PSYCHIATRIC GENETICS, 1998, 8 (04) :207-212
[6]  
ROFF DA, 1989, MOL BIOL EVOL, V6, P539
[7]  
Shabanov P.D., 1998, BIOL ALKOGOLIZMA