A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

被引：84

作者：

Holbach, M

Zheng, XL

Burd, C

Jones, CW

Weck, M ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[2] Georgia Inst Technol, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 07期

关键词：

D O I：

10.1021/jo052614y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1: 1: 1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.

引用

页码：2903 / 2906

页数：4

共 28 条

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