Facile and efficient synthesis of 4′-thioxo-1′,3,3′,4,4′,6′-hexahydro-1H,2′H-spiro(naphthalene-2,5′-pyrimidin)1-ones in a three-component Mannich-type reaction

被引：8

作者：

Jagodzinski, Tadeusz S. ^{[1
]}

Westerlich, Slawomir ^{[1
]}

机构：

[1] West Pomerania Univ Technol, Inst Chem & Environm Protect, Aleja Piastow 42, PL-71065 Szczecin, Poland

来源：

ARKIVOC | 2013年

关键词：

Mannich reaction; thioamides; spirohexahydropyrimidines; HEXAHYDROPYRIMIDINES; DERIVATIVES; CYCLIZATION; THIOAMIDES;

D O I：

10.3998/ark.5550190.p007.912

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Spirohexahydropyrimidines were obtained in the one-pot three-component reaction of the tetralone-derived thioamides, amines and formaldehyde with alcoholic hydrogen chloride as the catalyst.

引用

页码：294 / 303

页数：10

共 34 条

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