Recent advances in combinatorial chemistry applied to development of anti-HIV drugs

被引：11

作者：

Pettersson, S

Clotet-Codina, I

Esté, JA

Borrell, JI

Teixidó, J

机构：

[1] Univ Ramon Llull, IQS, GEM, E-08017 Barcelona, Spain

[2] Univ Autonoma Barcelona, Hosp Univ Germans Trias & Pujol, Lab Retrovirol IrsiCaixa, Badalona 08916, Spain

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2006年 / 6卷 / 01期

关键词：

combinatorial chemistry; synthesis; anti-HIV drugs; high throughput screening;

D O I：

10.2174/138955706775197820

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.

引用

页码：91 / 108

页数：18

共 111 条

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