Respiratory motion correction in 3-D PET data with advanced optical flow algorithms

被引:129
作者
Dawood, Mohammad [1 ]
Buether, Florian [2 ]
Jiang, Xiaoyi [1 ]
Schaefers, Klaus P. [2 ]
机构
[1] Univ Munster, Dept Math & Comp Sci, D-48149 Munster, Germany
[2] Univ Hosp Munster, Dept Nucl Med, D-48149 Munster, Germany
关键词
gating; motion correction; optical flow; positron emission tomography (PET); positron emission tomography/computed tomography (PET/CT);
D O I
10.1109/TMI.2008.918321
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
The problem of motion is well known in positron emission tomography (PET) studies. The PET images are formed over an elongated period of time. As the patients cannot hold breath during the PET acquisition, spatial blurring and motion artifacts are the natural result. These may lead to wrong quantification of the radioactive uptake. We present a solution to this problem by respiratory-gating the PET data and correcting the PET images for motion with optical flow algorithms. The algorithm is based on the combined local and global optical flow algorithm with modifications to allow for discontinuity preservation across organ boundaries and for application to 3-D volume sets. The superiority of the algorithm over previous work is demonstrated on software phantom and real patient data.
引用
收藏
页码:1164 / 1175
页数:12
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