Synthesis of graphene quantum dots and their applications in drug delivery

被引：202
|
作者：
Zhao, Changhong [1 ,2 ]
Song, Xuebin [1 ]
Liu, Ya [2 ]
Fu, Yifeng [2 ]
Ye, Lilei [3 ]
Wang, Nan [3 ]
Wang, Fan [1 ]
Li, Lu [1 ]
Mohammadniaei, Mohsen [4 ]
Zhang, Ming [4 ]
Zhang, Qiqing [1 ]
Liu, Johan [2 ,5 ]
机构：
[1] Xinxiang Med Univ, Sch Life Sci & Technol, Xinxiang 453003, Henan, Peoples R China
[2] Chalmers Univ Technol, Dept Microtechnol & Nanosci, Elect Mat & Syst Lab, S-41296 Gothenburg, Sweden
[3] SHT Smart High Tech AB, S-41133 Gothenburg, Sweden
[4] Tech Univ Denmark, Dept Hlth Technol, DK-2800 Lyngby, Denmark
[5] Shanghai Univ, Sch Automat & Mech Engn, SMIT Ctr, 20 Chengzhong Rd,Box 808, Shanghai 201800, Peoples R China
来源：
JOURNAL OF NANOBIOTECHNOLOGY | 2020年 / 18卷 / 01期
基金：
美国国家科学基金会; 中国国家自然科学基金;
关键词：
Graphene quantum dots; Top-down; Bottom-up; Drug delivery; Delivery-release mode; ONE-POT SYNTHESIS; MICROWAVE-ASSISTED SYNTHESIS; IN-SITU SYNTHESIS; FACILE SYNTHESIS; CARBON NANOTUBES; UP-CONVERSION; PHYSICOCHEMICAL PROPERTIES; SUSTAINABLE SYNTHESIS; HYDROTHERMAL ROUTE; SENSING PROPERTIES;
D O I：
10.1186/s12951-020-00698-z
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.
引用
收藏
页数：32
相关论文
共 50 条
  • [1] Synthesis of graphene quantum dots and their applications in drug delivery
    Changhong Zhao
    Xuebin Song
    Ya Liu
    Yifeng Fu
    Lilei Ye
    Nan Wang
    Fan Wang
    Lu Li
    Mohsen Mohammadniaei
    Ming Zhang
    Qiqing Zhang
    Johan Liu
    Journal of Nanobiotechnology, 18
  • [2] Synthesis and applications of graphene quantum dots: a review
    Chen, Weifeng
    Lv, Guo
    Hu, Weimin
    Li, Dejiang
    Chen, Shaona
    Dai, Zhongxu
    NANOTECHNOLOGY REVIEWS, 2018, 7 (02) : 157 - 185
  • [3] Synthesis, Applications, and Prospects of Graphene Quantum Dots: A Comprehensive Review
    Ghaffarkhah, Ahmadreza
    Hosseini, Ehsan
    Kamkar, Milad
    Sehat, Ali Akbari
    Dordanihaghighi, Sara
    Allahbakhsh, Ahmad
    van der Kuur, Colin
    Arjmand, Mohammad
    SMALL, 2022, 18 (02)
  • [4] Spotlighting graphene quantum dots and beyond: Synthesis, properties and sensing applications
    Valappil, Manila Ozhukil
    Pillai, Vijayamohanan K.
    Alwarappan, Subbiah
    APPLIED MATERIALS TODAY, 2017, 9 : 350 - 371
  • [5] Technical synthesis and biomedical applications of graphene quantum dots
    Li, Keheng
    Liu, Wei
    Ni, Yao
    Li, Dapeng
    Lin, Dongmei
    Su, Zhiqiang
    Wei, Gang
    JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (25) : 4811 - 4826
  • [6] Graphene quantum dots: Background, synthesis methods, and applications as nanocarrier in drug delivery and cancer treatment: An updated review
    Karami, Mohammad Hossein
    Abdouss, Majid
    Rahdar, Abbas
    Pandey, Sadanand
    INORGANIC CHEMISTRY COMMUNICATIONS, 2024, 161
  • [7] Graphene Quantum Dots (GQDs) for Bioimaging and Drug Delivery Applications: A Review
    Biswas, Manik Chandra
    Islam, Md Tariqul
    Nandy, Pranab Kumar
    Hossain, Md Milon
    ACS MATERIALS LETTERS, 2021, 3 (06): : 889 - 911
  • [8] Graphene quantum dots from chemistry to applications
    Tian, P.
    Tang, L.
    Teng, K. S.
    Lau, S. P.
    MATERIALS TODAY CHEMISTRY, 2018, 10 : 221 - 258
  • [9] Nanocomposites of Carbon Quantum Dots and Graphene Quantum Dots: Environmental Applications as Sensors
    Kaur, Ajaypal
    Pandey, Komal
    Kaur, Ramandeep
    Vashishat, Nisha
    Kaur, Manpreet
    CHEMOSENSORS, 2022, 10 (09)
  • [10] Recent Advances in Graphene Quantum Dots: Synthesis, Properties, and Applications
    Haque, Enamul
    Kim, Jeonghun
    Malgras, Victor
    Reddy, Kakarla Raghava
    Ward, Alister C.
    You, Jungmok
    Bando, Yoshio
    Hossain, Md. Shahriar A.
    Yamauchi, Yusuke
    SMALL METHODS, 2018, 2 (10): : 1 - 14
12345