Synthesis of 2,5-Diarylpyrroles by Ligand-Free Palladium-Catalyzed CH Activation of Pyrroles in Ionic Liquids

被引：47

作者：

Ehlers, Peter ^{[1
,2
]}

Petrosyan, Andranik ^{[1
,2
,3
]}

Baumgard, Jens ^{[1
,2
]}

Jopp, Stefan ^{[1
,2
]}

Steinfeld, Norbert ^{[2
]}

Ghochikyan, Tariel V. ^{[3
]}

Saghyan, Ashot S. ^{[3
,4
]}

Fischer, Christine ^{[2
]}

Langer, Peter ^{[1
,2
]}

机构：

[1] Univ Rostock, Inst Chem, D-18059 Rostock, Germany

[2] Univ Rostock eV, Leibniz Inst Katalyse, D-18059 Rostock, Germany

[3] Yerevan State Univ, Fac Chem, Yerevan 0025, Armenia

[4] NAS RA, Sci & Prod Ctr Armbiotechnol, Yerevan 0056, Armenia

来源：

CHEMCATCHEM | 2013年 / 5卷 / 08期

关键词：

C-H activation; heterocycles; ionic liquids; nanoparticles; palladium; CROSS-COUPLING REACTIONS; DIRECT ARYLATION; HECK REACTIONS; ARYL BROMIDES; COMPLEXES; POTENT; FUNCTIONALIZATION; DERIVATIVES; MECHANISM; ACIDS;

D O I：

10.1002/cctc.201300099

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The palladium-catalyzed CH activation and arylation of N-methylpyrrole and N-phenylpyrrole allowed a convenient synthesis of diarylpyrroles. The reactions were performed by using tetrabutylammonium acetate as an ionic solvent, which allowed for the application of a ligand-free catalytic system by using simple palladium salts or polyvinylpyrrolidone-stabilized palladium nanoparticles as the catalyst.

引用

页码：2504 / 2511

页数：8

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