A Perspective on Recurrent Vertigo

被引：14

作者：

Gacek, Richard R. ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Otolaryngol Head & Neck Surg, Worcester, MA 01655 USA

来源：

ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY HEAD AND NECK SURGERY | 2013年 / 75卷 / 02期

关键词：

Vertigo; Viral etiology; Positional vertigo; PAROXYSMAL POSITIONAL VERTIGO; HERPES-SIMPLEX-VIRUS; SPONTANEOUS OTOACOUSTIC EMISSIONS; DELAYED ENDOLYMPHATIC HYDROPS; EVOKED MYOGENIC POTENTIALS; MENIERES-DISEASE; VESTIBULAR NEURITIS; CUPULAR DEPOSITS; VIRAL NEUROPATHY; GUINEA PIG;

D O I：

10.1159/000348710

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The recurrent nature of the 3 most common vestibulopathies suggests a recurrent cause. Histopathology in temporal bones from patients with these syndromes - vestibular neuronitis (VN, n = 7), Meniere's disease (MD, n = 8) and benign paroxysmal positional vertigo (BPPV, n = 5) - shows focal degeneration of vestibular nerve axons and degenerated nearby facial nerve meatal ganglion cells. Transmission electron microscopic confirmation of intracytoplasmic viral particles in surgically excised vestibular nerves from patients with VN and MD support a viral etiology in these vestibulopathies. Antiviral treatment of these syndromes in a series of 211 patients with a 3- to 8-year follow-up resulted in complete control of vertigo in VN (88%), MD (90%) and BPPV (60%). Copyright (C) 2013 S. Karger AG, Basel

引用

页码：91 / 107

页数：17

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