Neutrophilic panniculitis developing after treatment of metastatic melanoma with vemurafenib

被引：31
|
作者：
Kim, Gene H. [1 ,2 ]
Levy, Alan [3 ]
Compoginis, Goli [1 ,3 ]
机构：
[1] Univ So Calif, Dept Dermatol, Los Angeles, CA USA
[2] Univ So Calif, Dept Pathol, Los Angeles, CA 90089 USA
[3] Levy Dermatol, Memphis, TN USA
来源：
JOURNAL OF CUTANEOUS PATHOLOGY | 2013年 / 40卷 / 07期
关键词：
drug reaction; melanoma; panniculitis; vemurafenib; BRAF; GENETICS;
D O I：
10.1111/cup.12149
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Vemurafenib is an inhibitor of BRAF and is used to treat patients with metastatic melanoma who carry a V600E BRAF mutation. Recently, four patients have been described in the literature who developed a neutrophilic panniculitis following treatment with a BRAF inhibitor. We present an additional case and review the clinical findings of the cases reported to date.
引用
收藏
页码：667 / 669
页数：3
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