Efficacy of florfenicol injection in the treatment of Mycoplasma hyopneumoniae induced respiratory disease in pigs

被引：14

作者：

Sacristan, R. Del Pozo ^{[1
]}

Thiry, J. ^{[2
]}

Vranckx, K. ^{[3
]}

Rodriguez, A. Lopez ^{[1
]}

Chiers, K. ^{[3
]}

Haesebrouck, F. ^{[3
]}

Thomas, E. ^{[4
]}

Maes, D. ^{[1
]}

机构：

[1] Univ Ghent, Fac Vet Med, Dept Reprod Obstet & Herd Hlth, B-9820 Merelbeke, Belgium

[2] Intervet Pharma R&D, F-49071 Beaucouze, France

[3] Univ Ghent, Fac Vet Med, Dept Pathol Bacteriol & Avian Dis, B-9820 Merelbeke, Belgium

[4] Intervet Innovat GmbH, D-55270 Schwabenheim, Germany

来源：

VETERINARY JOURNAL | 2012年 / 194卷 / 03期

关键词：

Pigs; Mycoplasma hyopneumoniae; Florfenicol; Treatment; PCR ASSAY; PNEUMONIA; BACTERIA;

D O I：

10.1016/j.tvjl.2012.04.015

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

This study investigated the efficacy of a single intramuscular injection of a new formulation of florfenicol to treat clinical respiratory disease following experimental Mycoplasma hyopneumoniae infection. M. hyopneumoniae-free piglets were allocated to three groups, namely, a treatment group (TG) and a positive control group (PCG), which were both inoculated endotracheally with a highly virulent isolate of M. hyopneumoniae, and a negative control group. At the onset of clinical disease, the TG received a single injection of florfenicol (30 mg/kg). All pigs were euthanased 4 weeks post-infection. Clinical symptoms were significantly reduced in the TG in comparison with the PCG. Average daily gain, feed conversion ratio, mortality and lung lesions were improved in the TG compared to the PCG, but the differences were not statistically significant. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：420 / 422

页数：3

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