SYNTHETIC STUDIES ON NATURAL PTERIN GLYCOSIDES

被引：4
作者：
Hanaya, Tadashi [1 ]
Yamamoto, Hiroshi [2 ]
机构：
[1] Okayama Univ, Fac Sci, Grad Sch Nat Sci & Technol,Dept Chem, Kita Ku, Tsushima, Okayama 7008530, Japan
[2] Shujitsu Univ, Sch Pharm, Naka Ku, Nishigawara, Okayama 7038516, Japan
来源：
HETEROCYCLES | 2012年 / 85卷 / 10期
关键词：
Pterin Glycoside; Pteridine; Glycosylation; Biopterin; Protecting Group; BIOPTERIN-ALPHA-GLUCOSIDE; NITRIC-OXIDE SYNTHASE; EFFICIENT SYNTHESIS; 1ST SYNTHESIS; PTERIDINES; CHEMISTRY; NEOPTERIN; ACID; IDENTIFICATION; TEPIDOPTERIN;
D O I：
10.3987/REV-12-742
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Some pterins having various kind of sugars attached to the hydroxyalkyl side-chain at C-6 are known to occur in certain prokaryotes as exemplified by 2'-O-(alpha-D-glucopyranosyl)biopterin isolated from various kinds of cyanobacteria. A synthetic exploration of various types of glycosides of biopterin and related pterins has been undertaken owing to a marked interest in their physiological functions and biological activities as well as the structural proof of those natural products. This review summarizes our synthetic studies on natural pterin glycosides by employing the appropriately protected N-2-(N,N-dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]pterin derivatives as glycosyl accepters.
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页码：2375 / +
页数：17
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