Long-lasting successful cerebral response with sorafenib in advanced renal cell carcinoma

被引：33

作者：

Valcamonico, Francesca ^{[1
]}

Ferrari, Vittorio ^{[1
]}

Amoroso, Vito ^{[1
]}

Rangoni, Giovanni ^{[1
]}

Simoncini, Edda ^{[1
]}

Marpicati, Patrizia ^{[1
]}

Vassalli, Lucia ^{[1
]}

Grisanti, Salvatore ^{[1
]}

Marini, Giovanni ^{[1
]}

机构：

[1] Spedali Civili Brescia, Dept Med Oncol, Brescia, Italy

来源：

JOURNAL OF NEURO-ONCOLOGY | 2009年 / 91卷 / 01期

关键词：

Advanced renal cell carcinoma; Sorafenib; Brain metastases; ANTITUMOR-ACTIVITY; TRIAL;

D O I：

10.1007/s11060-008-9676-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report the case of a 75-year old woman who received sorafenib (Nexavar (R), Bayer Pharmaceuticals Corporation, West Haven, CT) for a CNS relapse of clear cell renal cell carcinoma. After four months of sorafenib treatment, a brain magnetic resonance imaging showed 95%-volumetric regression of cerebral metastasis. To the best of our knowledge, this is the first almost complete resolution of brain metastases in renal cell carcinoma treated with sorafenib that has been described.

引用

页码：47 / 50

页数：4

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