Two-Year Clinical Outcomes Between Prediabetic and Diabetic Patients With STEMI and Multivessel Disease Who Underwent Successful PCI Using Drug-Eluting Stents

被引：8

作者：

Kim, Yong Hoon ^{[1
]}

Her, Ae-Young ^{[1
]}

Jeong, Myung Ho ^{[2
]}

Kim, Byeong-Keuk ^{[3
]}

Hong, Sung-Jin ^{[3
]}

Kim, Seunghwan ^{[4
]}

Ahn, Chul-Min ^{[3
]}

Kim, Jung-Sun ^{[3
]}

Ko, Young-Guk ^{[3
]}

Choi, Donghoon ^{[3
]}

Hong, Myeong-Ki ^{[3
]}

Jang, Yangsoo ^{[3
]}

机构：

[1] Kangwon Natl Univ, Dept Internal Med, Div Cardiol, Sch Med, 156 Baengnyeong Rd, Chunchon 24289, Gangwon, South Korea

[2] Chonnam Natl Univ Hosp, Dept Cardiol, Gwangju, South Korea

[3] Yonsei Univ, Severance Cardiovasc Hosp, Div Cardiol, Coll Med, Seoul, South Korea

[4] Inje Univ, Haeundae Paik Hosp, Div Cardiol, Coll Med, Busan, South Korea

来源：

ANGIOLOGY | 2021年 / 72卷 / 01期

关键词：

prediabetes; type; 2; diabetes; acute myocardial infarction; ACUTE MYOCARDIAL-INFARCTION; CORONARY-ARTERY-DISEASE; ST-SEGMENT ELEVATION; ABNORMAL GLUCOSE REGULATION; COMPLETE REVASCULARIZATION; TEMPORAL TRENDS; SHORT-TERM; MORTALITY; INTERVENTION; MELLITUS;

D O I：

10.1177/0003319720949311

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

To evaluate clinical implication of prediabetes, we compared a 2-year major clinical outcome including patient-oriented composite outcomes (POCOs), stent thrombosis (ST), and stroke between prediabetes and diabetes in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD). A total of 4097 patients with STEMI and MVD (normoglycemia [group A: 1001], prediabetes [group B: 1518], and diabetes [group C: 1578]) who received drug-eluting stents were evaluated. Patient-oriented composite outcomes were defined as all-cause death, recurrent myocardial infarction (MI), or any repeat revascularization. The cumulative incidences of POCOs, ST, and stroke were similar between groups B and C. The cumulative incidences of all-cause death (adjusted hazard ratio [aHR]: 1.483; 95% CI: 1.027-2.143;P= .036) and all-cause death or MI (aHR: 1.429, 95% CI: 1.034-1.974;P= .031) were higher in group B than in group A. The cumulative incidences of all-cause death (aHR: 1.563; 95% CI: 1.089-2.243;P= .015), cardiac death (aHR: 1.661; 95% CI: 1.123-2.457;P= .011), and all-cause death or MI were higher in group C than in group A. In conclusion, prediabetes could potentially have a similar impact as diabetes on major clinical outcomes in patients with STEMI and MVD.

引用

页码：50 / 61

页数：12

共 43 条

[1] Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease - The bypass angioplasty revascularization investigation (BARI) [J].

Alderman, E ;

Bourassa, M ;

Brooks, MM ;

Califf, R ;

Chaitman, B ;

Detre, K ;

Faxon, DP ;

Feit, F ;

Frye, RL ;

Hardison, RM ;

Holmes, D ;

Holubkov, R ;

Kouchoukos, N ;

Krone, R ;

Rogers, W ;

Rosen, AD ;

Schaff, H ;

Schwartz, L ;

Siewers, AS ;

Sopko, G ;

SuttonTyrrell, K ;

Whitlow, P .

CIRCULATION, 1997, 96 (06) :1761-1769

[2] Cardiovascular and renal burdens of prediabetes in the USA: analysis of data from serial cross-sectional surveys, 1988-2014 [J].

Ali, Mohammed K. ;

Bullard, Kai McKeever ;

Saydah, Sharon ;

Imperatore, Giuseppina ;

Gregg, Edward W. .

LANCET DIABETES & ENDOCRINOLOGY, 2018, 6 (05) :392-403

[3]

Amer Diabet Assoc, 2011, DIABETES CARE, V34, pS11, DOI [10.2337/dc11-S062, 10.2337/dc12-s011, 10.2337/dc11-S011, 10.2337/dc10-S062, 10.2337/dc10-S011, 10.2337/dc13-S067, 10.2337/dc14-S081, 10.2337/dc13-S011, 10.2337/dc12-s064]

[4] Prevalence of glucose abnormalities among patients presenting with an acute myocardial infarction [J].