The biosynthesis of bisvertinolone: evidence for oxosorbicillinol as a direct precursor

被引：21
作者：
Abe, N [1 ]
Arakawa, T [1 ]
Hirota, A [1 ]
机构：
[1] Univ Shizuoka, Sch Food & Nutr Sci, Shizuoka 4228526, Japan
来源：
CHEMICAL COMMUNICATIONS | 2002年 / 03期
关键词：
D O I：
10.1039/b109505f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Biosynthetic incorporation of labeled sodium acetate into oxosorbicillinol in Trichoderma sp. USF-2690 suggests that oxosorbicillinol is derived from six acetate units, and subsequent bioconversion of the labeled oxosorbicillinol to bisvertinolone in the fermentation of the strain suggests that bisvertinolone is biosynthesized from oxosorbicillinol and sorbicillinol in a Michael-type reaction.
引用
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页码：204 / 205
页数：2
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