Synthesis of trifluoromethyl-substituted bi- and terphenyls by site-selective Suzuki-Miyaura reactions of various dihalogenated trifluoromethyl-benzene derivatives

被引：11

作者：

Ali, Iftikhar ^{[1
,2
]}

Siyo, Baraa ^{[1
]}

Hassan, Zahid ^{[1
]}

Malik, Imran ^{[1
,3
]}

Ullah, Ihsan ^{[1
,4
]}

Ali, Asad ^{[1
,4
]}

Nawaz, Muhammad ^{[1
]}

Iqbal, Jamshed ^{[5
]}

Patonay, Tamas ^{[6
]}

Villinger, Alexander ^{[1
]}

Langer, Peter ^{[1
,7
]}

机构：

[1] Univ Rostock, Inst Chem, D-18059 Rostock, Germany

[2] Karakoram Int Univ, Dept Chem, Gilgit Baltistan, Pakistan

[3] COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan

[4] Abdul Wali Khan Univ, Dept Chem, Mardan, Kpk, Pakistan

[5] COMSATS Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan

[6] Univ Debrecen, Dept Organ Chem, H-4032 Debrecen, Hungary

[7] Univ Rostock eV, Leibniz Inst Katalyse, D-18059 Rostock, Germany

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2013年 / 145卷

关键词：

Catalysis; Palladium; Suzuki reaction; Organofluorine compounds; Site-selectivity; CROSS-COUPLING REACTIONS; CHLORIDES;

D O I：

10.1016/j.jfluchem.2012.11.005

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A variety of trifluoromethylated bi- and terphenyls were prepared by site-selective Suzuki-Miyaura cross-coupling reactions of various dihalogenated trifluoromethyl-substituted benzene derivatives. The reactions proceed with excellent site-selectivities. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：18 / 34

页数：17

共 38 条

[1] The directed ortho metalation -: cross coupling symbiosis.: Regioselective methodologies for biaryls and heterobiaryls.: Deployment in aromatic and heteroaromatic natural product synthesis [J].