Elevated taurine and glutamate in cerebral juvenile xanthogranuloma on MR spectroscopy

被引：4

作者：

Matsubara, Ken ^{[1
]}

Mori, Harushi ^{[2
,3
]}

Hirai, Nozomi ^{[1
]}

Yasukawa, Kumi ^{[1
]}

Honda, Takafumi ^{[1
]}

Takanashi, Jun-ichi ^{[1
]}

机构：

[1] Tokyo Womens Med Univ, Dept Pediat, Yachiyo Med Ctr, 477-96 Owadashinden, Yachiyo 2768524, Japan

[2] Univ Tokyo, Grad Sch, Dept Radiol, Tokyo, Japan

[3] Univ Tokyo, Fac Med, Tokyo, Japan

来源：

BRAIN & DEVELOPMENT | 2016年 / 38卷 / 10期

关键词：

Juvenile xanthogranuloma; MR spectroscopy; Taurine; Glutamate; IN-VIVO; QUANTITATION; CHILDHOOD; LCMODEL;

D O I：

10.1016/j.braindev.2016.07.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MRI in a 2-year-old female presenting afebrile seizures and left blepharoptosis revealed multiple well-marginated round-shaped lesions, isointensity to gray matter on T1- and T2-weighted images with homogenously reduced diffusion and diffuse contrast enhancement. MRS revealed elevation of taurine, choline and glutamate, and reduction of N-acetylaspartate. A brain biopsy confirmed a diagnosis of juvenile xanthogranuloma (JXG). JXG should be considered when MR spectroscopy shows elevated taurine and glutamate, which has only previously been reported in medulloblastomas. (C) 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

引用

页码：964 / 967

页数：4

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