Mineralocorticoid Receptor Antagonists Displace Cortisol, not Aldosterone, from the Human Heart

被引:0
|
作者
Iqbal, Javaid [1 ]
Andrew, Ruth [1 ]
Cruden, Nicholas [1 ]
Kenyon, Christopher [1 ]
Hughes, Katherine [1 ]
Hadoke, Patrick [1 ]
Newby, David [1 ]
Walker, Brian [1 ]
机构
[1] Univ Edinburgh, Cntr Cardiovasc Sci, Edinburgh, Midlothian, Scotland
关键词
Aldosterone; Heart failure;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
14332
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Aldosterone, Mineralocorticoid Receptor and the Metabolic Syndrome: Role of the Mineralocorticoid Receptor Antagonists
    Ronconi, Vanessa
    Turchi, Federica
    Appolloni, Gloria
    di Tizio, Valentina
    Boscaro, Marco
    Giacchetti, Gilberta
    CURRENT VASCULAR PHARMACOLOGY, 2012, 10 (02) : 238 - 246
  • [2] Aldosterone, mineralocorticoid receptor, and heart failure
    Messaoudi, Smail
    Azibani, Feriel
    Delcayre, Claude
    Jaisser, Frederic
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2012, 350 (02) : 266 - 272
  • [3] Displacement of Cortisol From Human Heart by Acute Administration of a Mineralocorticoid Receptor Antagonist
    Iqbal, Javaid
    Andrew, Ruth
    Cruden, Nicholas L.
    Kenyon, Christopher J.
    Hughes, Katherine A.
    Newby, David E.
    Hadoke, Patrick W. F.
    Walker, Brian R.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (03): : 915 - 922
  • [4] Aldosterone and Mineralocorticoid Receptor Antagonists Modulate Elastin and Collagen Deposition in Human Skin
    Mitts, Thomas F.
    Bunda, Severa
    Wang, Yanting
    Hinek, Aleksander
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2010, 130 (10) : 2396 - 2406
  • [5] Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone
    Maeoka, Yujiro
    Su, Xiao-Tong
    Wang, Wen-Hui
    Duan, Xin-Peng
    Sharma, Avika
    Li, Na
    Staub, Olivier
    McCormick, James A.
    Ellison, David H.
    HYPERTENSION, 2022, 79 (07) : 1423 - 1434
  • [6] Mineralocorticoid receptor antagonists for heart failure
    Richards, Arthur Mark
    EXPERT OPINION ON PHARMACOTHERAPY, 2011, 12 (18) : 2801 - 2815
  • [7] Human aldosterone receptor and mineralocorticoid response
    Govindan, MV
    Warriar, N
    FASEB JOURNAL, 2005, 19 (04): : A298 - A298
  • [8] Targeting aldosterone to improve cardiorenal outcomes: from nonsteroidal mineralocorticoid receptor antagonists to aldosterone synthase inhibitors
    Helmeczi, Wryan
    Hundemer, Gregory L.
    CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2025, 34 (03): : 241 - 246
  • [9] Aldosterone Synthase Inhibitors and Mineralocorticoid Receptor Antagonists: Competitors or Collaborators?
    Pitt, Bertram
    Williams, Gordon H.
    CIRCULATION, 2024, 149 (06) : 414 - 416
  • [10] Heart failure: the role for mineralocorticoid receptor antagonists
    Pitt, Bertram
    SWISS MEDICAL WEEKLY, 2014, 144