Facile synthesis of biarylmethanes and tetrasubstituted arenes via a base-mediated [3+3] benzannulation reaction of Morita-Baylis-Hillman adducts and unsaturated sulfones

被引：14
|
作者：
Yadav, Deepak [1 ,2 ]
Sharma, Sunil K. [2 ]
Menon, Rajeev S. [1 ]
机构：
[1] Cent Univ Haryana, Dept Chem, Mahendergarh 123029, Haryana, India
[2] Univ Delhi, Dept Chem, Delhi 110007, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 16期
关键词：
CROSS-COUPLING REACTIONS; REGIOSELECTIVE SYNTHESIS; ANNULATION; STRATEGY; ARYL; CONSTRUCTION;
D O I：
10.1039/c9ob00214f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile DBU-mediated [3 + 3] benzannulation reaction of 1,3-bis-sulfonyl propenes and Morita-BaylisHillman (MBH) bromides is described. The benzannulation reaction afforded bis-sulfonyl biarylmethanes/arenes with complete regioselectivity. The products may be converted readily into corresponding benzophenones via site-selective benzylic oxidation.
引用
收藏
页码：4073 / 4076
页数：4
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