A Mild Chemoselective Ru-Catalyzed Reduction of Alkynes, Ketones, and Nitro Compounds

被引：87

作者：

Schabel, Tobias ^{[1
]}

Belger, Christian ^{[1
]}

Plietker, Bernd ^{[1
]}

机构：

[1] Univ Stuttgart, Inst Organ Chem, DE-70569 Stuttgart, Germany

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 11期

关键词：

HYDROGEN-TRANSFER REACTIONS; FORMIC-ACID; WATER; NITROARENES; COMPLEXES; OLEFINS; RUTHENIUM; ALDEHYDES; ALKENES; ZINC;

D O I：

10.1021/ol401185t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chemoselective reduction of alkyne, ketones, or nitro groups using (Ph3P)(3)RuCl2 as an inexpensive catalyst and Zn/water as a stoichiometric reductant is reported. Depending on the nature of the additive and the temperature, good chemoselectivities were observed allowing, e.g., for the selective reduction of a nitro group in the presence of a ketone or an alkyne.

引用

页码：2858 / 2861

页数：4

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