Medical progress: Multiple sclerosis - The plaque and its pathogenesis

被引:1277
作者
Frohman, EM
Racke, MK
Raine, CS
机构
[1] Univ Texas, SW Med Ctr, Dept Neurol, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Dept Ophthalmol, Dallas, TX 75390 USA
[3] Univ Texas, SW Med Ctr, Ctr Immunol, Dallas, TX 75390 USA
[4] Albert Einstein Coll Med, Div Neuropathol, Dept Pathol & Neurol, Bronx, NY 10467 USA
关键词
D O I
10.1056/NEJMra052130
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:942 / 955
页数:14
相关论文
共 80 条
  • [1] ENCEPHALITOGENIC T-CELLS IN THE B10.PL MODEL OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAE) ARE OF THE TH-1 LYMPHOKINE SUBTYPE
    ANDO, DG
    CLAYTON, J
    KONO, D
    URBAN, JL
    SERCARZ, EE
    [J]. CELLULAR IMMUNOLOGY, 1989, 124 (01) : 132 - 143
  • [2] bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS
    Arnett, HA
    Fancy, SPJ
    Alberta, JA
    Zhao, C
    Plant, SR
    Kaing, S
    Raine, CS
    Rowitch, DH
    Franklin, RJM
    Stiles, CD
    [J]. SCIENCE, 2004, 306 (5704) : 2111 - 2115
  • [3] INHIBITION OF T-CELL RESPONSES BY ACTIVATED HUMAN CD8+ T-CELLS IS MEDIATED BY INTERFERON-GAMMA AND IS DEFECTIVE IN CHRONIC PROGRESSIVE MULTIPLE-SCLEROSIS
    BALASHOV, KE
    KHOURY, SJ
    HAFLER, DA
    WEINER, HL
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (06) : 2711 - 2719
  • [4] Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    Barnett, MH
    Prineas, JW
    [J]. ANNALS OF NEUROLOGY, 2004, 55 (04) : 458 - 468
  • [5] Axonal protection using flecainide in experimental autoimmune encephalomyelitis
    Bechtold, DA
    Kapoor, R
    Smith, KJ
    [J]. ANNALS OF NEUROLOGY, 2004, 55 (05) : 607 - 616
  • [6] Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
    Bettelli, E
    Sullivan, B
    Szabo, SJ
    Sobel, RA
    Glimcher, H
    Kuchroo, VK
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (01) : 79 - 87
  • [7] Bielekova B, 2000, NAT MED, V6, P1412
  • [8] Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
    Bielekova, B
    Goodwin, B
    Richert, N
    Cortese, I
    Kondo, T
    Afshar, G
    Gran, B
    Eaton, J
    Antel, J
    Frank, JA
    McFarland, HF
    Martin, R
    [J]. NATURE MEDICINE, 2000, 6 (10) : 1167 - 1175
  • [9] Acute axonal injury in multiple sclerosis -: Correlation with demyelination and inflammation
    Bitsch, A
    Schuchardt, J
    Bunkowski, S
    Kuhlmann, T
    Brück, W
    [J]. BRAIN, 2000, 123 : 1174 - 1183
  • [10] Bjartmar C, 2000, ANN NEUROL, V48, P893, DOI 10.1002/1531-8249(200012)48:6<893::AID-ANA10>3.3.CO