Cellular mechanisms of calcium and vitamin D in the inhibition of colorectal carcinogenesis

被引：167
作者：
Lamprecht, SA [1 ]
Lipkin, M [1 ]
机构：
[1] Strang Canc Prevent Ctr, New York, NY 10021 USA
来源：
CANCER PREVENTION: MOLECULAR MECHANISMS TO CLINICAL APPLICATIONS | 2001年 / 952卷
关键词：
calcium; vitamin D; colon cancer;
D O I：
10.1111/j.1749-6632.2001.tb02729.x
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Convincing evidence is available showing that dietary calcium and vitamin D impede the development of colonic carcinogenesis. The major cellular modes of action of calcium and vitamin D which can contribute to the inhibition of colonic neoplasia are reviewed in this article. These consist of complex series of signaling events induced by the chemopreventive agents acting at various tiers of colonic cell organization.
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收藏
页码：73 / 87
页数：15
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