Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance

被引：28
|
作者：
Wang, SM
Ryder, H
Pretswell, I
Depledge, P
Milton, J
Hancox, TC
Dale, I
Dangerfield, W
Charlton, P
Faint, R
Dodd, R
Hassan, S
机构：
[1] Xenova Ltd, Dept Med Chem, Slough SL1 4NL, Berks, England
[2] Xenova Ltd, Dept Pharmacol, Slough SL1 4NL, Berks, England
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 04期
关键词：
D O I：
10.1016/S0960-894X(01)00804-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The syntheses and SAR studies of various quinazolinone compounds are described for the dual inhibition of Pgp and MRP1 in multidrug resistance. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：571 / 574
页数：4
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