Perfumers' expertise induces structural reorganization in olfactory brain regions

被引：67
作者：
Delon-Martin, Chantal [1 ,2 ]
Plailly, Jane [3 ]
Fonlupt, Pierre [4 ]
Veyrac, Alexandra [5 ]
Royet, Jean-Pierre [3 ]
机构：
[1] INSERM, Inst Neurosci, U836, Equipe Neuroimagerie & Perfus Cerebrale, F-38043 Grenoble 9, France
[2] Univ Grenoble 1, Grenoble Inst Neurosci, F-38043 Grenoble 9, France
[3] Univ Lyon 1, CNRS, UMR 5292, INSERM,U1028,Olfact Coding Memory Team, F-69366 Lyon, France
[4] Univ Lyon 1, CNRS, UMR 5292, INSERM,U1028,Brain Dynam & Cognit Team, F-69675 Bron, France
[5] Univ Paris 11, Ctr Neurosci Paris Sud, CNRS, UMR 8195, F-91905 Orsay, France
来源：
NEUROIMAGE | 2013年 / 68卷
关键词：
Olfaction; Perfumer; Expertise; Gray-matter volume; Voxel-based morphometry; Structural reorganization; VOXEL-BASED MORPHOMETRY; MEDIAL PREFRONTAL CORTEX; HUMAN ORBITOFRONTAL CORTEX; NEWLY GENERATED NEURONS; GRAY-MATTER; BULB VOLUME; MACAQUE MONKEY; ARCHITECTONIC SUBDIVISION; NEURAL REPRESENTATIONS; PARKINSONS-DISEASE;
D O I：
10.1016/j.neuroimage.2012.11.044
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The human brain's ability to adapt to environmental changes is obvious in specific sensory domains of experts, and olfaction is one of the least investigated senses. As we have previously demonstrated that olfactory expertise is related to functional brain modifications, we investigated here whether olfactory expertise is also coupled with structural changes. We used voxel-based morphometry to compare the gray-matter volume in student and professional perfumers, as well as untrained control subjects, and accounted for all methodological improvements that have been recently developed to limit possible errors associated with image processing. In all perfumers, we detected an increase in gray-matter volume in the bilateral gyrus rectus/medial orbital gyrus (GR/MOG), an orbitofrontal area that surrounds the olfactory sulcus. In addition, gray-matter volume in the anterior PC and left GR/MOG was positively correlated with experience in professional perfumers. We concluded that the acute olfactory knowledge acquired through extensive olfactory training leads to the structural reorganization of olfactory brain areas. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码：55 / 62
页数：8
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