Encapsulation of resveratrol using food-grade concentrated double emulsions: Emulsion characterization and rheological behaviour

被引:66
作者
Matos, Maria [1 ]
Gutierrez, Gemma [1 ]
Martinez-Rey, Lemuel [1 ]
Iglesias, Olvido [1 ]
Pazos, Carmen [1 ]
机构
[1] Univ Oviedo, Dept Chem & Environm Engn, Julian Claveria 8, E-33006 Oviedo, Spain
关键词
Resveratrol; Double emulsion; Concentrated emulsion; Encapsulation efficiency; WATER MULTIPLE EMULSIONS; SURFACTANT CONCENTRATION; W/O/W EMULSIONS; OIL; STABILITY; BIOAVAILABILITY; DELIVERY; STABILIZATION; MECHANISMS; FORMULATION;
D O I
10.1016/j.jfoodeng.2018.01.007
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The aim of this work was to prepare concentrated water-in-oil-in-water (W-1/O/W-2) double emulsions to entrap resveratrol (RSV) with high encapsulation efficiency, good stability, and appropriate theological behaviour. W-1/O was formulated with an ethanol/water RSV solution (W-1) dispersed in Miglyol 812 (O) (20 vol%) with polyglycerol polyricinoleate as stabiliser. W-2 was a 2% w/v Tween 20 solution with and without sodium carboximethylcellulose as thickening agent. Different volumetric ratios (20/80 to 80/20) of W-1/O dispersed into W-2 were used. W-1/O/W-2 emulsions were characterized in terms of visual inspection, droplet size distribution, and stability. The rheology of these double emulsions was fully studied. Actual encapsulation efficiency was determined considering the non-encapsulated RSV recovery yield. The concentrated W-1/O/W-2 double emulsions with the optimum formulation showed high encapsulation efficiency (up to 58%), good storage stability, shear-thinning behaviour, and dominant elastic character, with 6.2 mg/L of encapsulated RSV. These double emulsions may be suitable for food applications. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:73 / 81
页数:9
相关论文
共 53 条
[31]   Resveratrol supplementation: Where are we now and where should we go? [J].
Novelle, Marta G. ;
Wahl, Devin ;
Dieguez, Carlos ;
Bernier, Michel ;
de Cabo, Rafael .
AGEING RESEARCH REVIEWS, 2015, 21 :1-15
[32]   RHEOLOGICAL BEHAVIOR OF CONCENTRATED SURFACTANT SOLUTIONS AND EMULSIONS [J].
PAL, R .
COLLOIDS AND SURFACES, 1992, 64 (3-4) :207-215
[33]   Rheology of simple and multiple emulsions [J].
Pal, Rajinder .
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2011, 16 (01) :41-60
[34]   Resveratrol: review on therapeutic potential and recent advances in drug delivery [J].
Pangeni, Rudra ;
Sahni, Jasjeet K. ;
Ali, Javed ;
Sharma, Shrestha ;
Baboota, Sanjula .
EXPERT OPINION ON DRUG DELIVERY, 2014, 11 (08) :1285-1298
[35]  
Park CI, 2003, KOREA-AUST RHEOL J, V15, P125
[36]   Water soluble inner aqueous phase markers as indicators of the encapsulation properties of water-in-oil-in-water emulsions stabilized with sodium caseinate [J].
Regan, Jonathan O' ;
Mulvihill, Daniel M. .
FOOD HYDROCOLLOIDS, 2009, 23 (08) :2339-2345
[37]   Emulsion catastrophic inversion from abnormal to normal morphology.: 5.: Effect of the water-to-oil ratio and surfactant concentration on the inversion produced by continuous stirring [J].
Rondón-González, M ;
Sadtler, V ;
Choplín, L ;
Salager, JL .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2006, 45 (09) :3074-3080
[38]   Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad? [J].
Saiko, Philipp ;
Szakmary, Akos ;
Jaeger, Walter ;
Szekeres, Thomas .
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2008, 658 (1-2) :68-94
[39]   Production of W/O/W (water-in-oil-in-water) multiple emulsions: droplet breakup and release of water [J].
Schuch, Anna ;
Deiters, Philipp ;
Henne, Julius ;
Koehler, Karsten ;
Schuchmann, Heike P. .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2013, 402 :157-164
[40]   Bioavailability of encapsulated resveratrol into nanoemulsion-based delivery systems [J].
Sessa, Mariarenata ;
Balestrieri, Maria Luisa ;
Ferrari, Giovanna ;
Servillo, Luigi ;
Castaldo, Domenico ;
D'Onofrio, Nunzia ;
Donsi, Francesco ;
Tsao, Rong .
FOOD CHEMISTRY, 2014, 147 :42-50