Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors

被引：25

作者：

Combs, Stephanie E. ^{[1
]}

Nagy, Monika ^{[1
]}

Edler, Lutz ^{[2
]}

Rausch, Renate ^{[2
]}

Bischof, Marc ^{[1
]}

Welzel, Thomas ^{[1
]}

Debus, Juergen ^{[1
]}

Schulz-Ertner, Daniela ^{[1
]}

机构：

[1] Univ Heidelberg Hosp, Dept Radiat Oncol, Heidelberg, Germany

[2] German Canc Res Ctr, Dept Biostat, D-6900 Heidelberg, Germany

来源：

RADIOTHERAPY AND ONCOLOGY | 2008年 / 88卷 / 02期

关键词：

anaplastic glioma; radiotherapy; chemotherapy; outcome;

D O I：

10.1016/j.radonc.2008.03.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Outcome after radiochemotherapy (RCHT) with temozolomide (TMZ) versus radiotherapy (RT) for WHO grade III astrocytic tumors was evaluated. No significant difference in overall survival or progression-free survival between both groups was calculated. RCHT seems not to result in an improved outcome. Further randomized studies are needed to support these results. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：177 / 182

页数：6

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