Antisense oligonucleotides (ASOs) in chronic hepatitis B infection: Opportunities and challenging the orthodoxy

被引:7
作者
Agarwal, Kosh [1 ]
Lok, James [1 ]
Gane, Ed [2 ]
机构
[1] Kings Coll Hosp London, Inst Liver Studies, London, England
[2] Univ Auckland, Auckland, New Zealand
关键词
BEPIROVIRSEN; DELIVERY; LIVER; HBV;
D O I
10.1016/j.jhep.2022.08.020
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:906 / 908
页数:3
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共 18 条
[1]   Efficacy and safety of vutrisiran for patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy: a randomized clinical trial [J].
Adams, David ;
Tournev, Ivailo L. ;
Taylor, Mark S. ;
Coelho, Teresa ;
Plante-Bordeneuve, Violaine ;
Berk, John L. ;
Gonzalez-Duarte, Alejandra ;
Gillmore, Julian D. ;
Low, Soon-Chai ;
Sekijima, Yoshiki ;
Obici, Laura ;
Chen, Chongshu ;
Badri, Prajakta ;
Arum, Seth M. ;
Vest, John ;
Polydefkis, Michael .
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2023, 30 (01) :18-26
[2]  
Aligos Therapeutics, 2022, AL DISC DEV ANT OL D
[3]   Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug [J].
Debacker, Alexandre J. ;
Voutila, Jon ;
Catley, Matthew ;
Blakey, David ;
Habib, Nagy .
MOLECULAR THERAPY, 2020, 28 (08) :1759-1771
[4]   Clinical Study of Single-Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B [J].
Gane, Edward ;
Yuen, Man-Fung ;
Kim, Dong Joon ;
Chan, Henry Lik-Yuen ;
Surujbally, Bernadette ;
Pavlovic, Vedran ;
Das, Sudip ;
Triyatni, Miriam ;
Kazma, Remi ;
Grippo, Joseph F. ;
Buatois, Simon ;
Lemenuel-Diot, Annabelle ;
Krippendorff, Ben-Fillippo ;
Mueller, Henrik ;
Zhang, Yuchen ;
Kim, Hyung Joon ;
Leerapun, Apinya ;
Lim, Tien Huey ;
Lim, Young-Suk ;
Tanwandee, Tawesak ;
Kim, Won ;
Cheng, Wendy ;
Hu, Tsung-Hui ;
Wat, Cynthia .
HEPATOLOGY, 2021, 74 (04) :1795-1808
[5]   Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1 [J].
Garrelfs, Sander F. ;
Frishberg, Yaacov ;
Hulton, Sally A. ;
Koren, Michael J. ;
O'Riordan, William D. ;
Cochat, Pierre ;
Deschenes, Georges ;
Shasha-Lavsky, Hadas ;
Saland, Jeffrey M. ;
van't Hoff, William G. ;
Fuster, Daniel G. ;
Magen, Daniella ;
Moochhala, Shabbir H. ;
Schalk, Gesa ;
Simkova, Eva ;
Groothoff, Jaap W. ;
Sas, David J. ;
Meliambro, Kristin A. ;
Lu, Jiandong ;
Sweetser, Marianne T. ;
Garg, Pushkal P. ;
Vaishnaw, Akshay K. ;
Gansner, John M. ;
McGregor, Tracy L. ;
Lieske, John C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (13) :1216-1226
[6]   Toll-like receptor control of the adaptive immune responses [J].
Iwasaki, A ;
Medzhitov, R .
NATURE IMMUNOLOGY, 2004, 5 (10) :987-995
[7]   Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo [J].
Javanbakht, Hassan ;
Mueller, Henrik ;
Walther, Johanna ;
Zhou, Xue ;
Lopez, Anais ;
Pattupara, Thushara ;
Blaising, Julie ;
Pedersen, Lykke ;
Albaek, Nanna ;
Jackerott, Malene ;
Shi, Tianlai ;
Ploix, Corinne ;
Driessen, Wouter ;
Persson, Robert ;
Ravn, Jacob ;
Young, John A. T. ;
Ottosen, Soren .
MOLECULAR THERAPY-NUCLEIC ACIDS, 2018, 11 :441-454
[8]  
Lim SG, 2022, J HEPATOL, V77, pS880
[9]   Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study [J].
Marcellin, Patrick ;
Gane, Edward ;
Buti, Maria ;
Afdhal, Nezam ;
Sievert, William ;
Jacobson, Ira M. ;
Washington, Mary Kay ;
Germanidis, George ;
Flaherty, John F. ;
Schall, Raul Aguilar ;
Bornstein, Jeff Rey D. ;
Kitrinos, Kathryn M. ;
Subramanian, G. Mani ;
McHutchison, John G. ;
Heathcote, E. Jenny .
LANCET, 2013, 381 (9865) :468-475
[10]   Hepatocellular carcinoma prediction beyond year 5 of oral therapy in a large cohort of Caucasian patients with chronic hepatitis B [J].
Papatheodoridis, George V. ;
Sypsa, Vana ;
Dalekos, George N. ;
Yurdaydin, Cihan ;
Van Boemmel, Florian ;
Buti, Maria ;
Calleja, Jose Luis ;
Chi, Heng ;
Goulis, John ;
Manolakopoulos, Spilios ;
Loglio, Alessandro ;
Voulgaris, Theodoros ;
Gatselis, Nikolaos ;
Keskin, Onur ;
Veelken, Rhea ;
Lopez-Gomez, Marta ;
Hansen, Bettina E. ;
Savvidou, Savvoula ;
Kourikou, Anastasia ;
Vlachogiannakos, John ;
Galanis, Kostas ;
Idilman, Ramazan ;
Esteban, Rafael ;
Janssen, Harry L. A. ;
Berg, Thomas ;
Lampertico, Pietro .
JOURNAL OF HEPATOLOGY, 2020, 72 (06) :1088-1096