The role of B cells in acute and chronic infections

被引:41
作者
Bachmann, MF [1 ]
Kopf, M [1 ]
机构
[1] Basel Inst Immunol, CH-4005 Basel, Switzerland
关键词
D O I
10.1016/S0952-7915(99)80053-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The important role of B cells in protection against secondary viral infections has been recognized for a long time. Recent evidence suggests that B cells are also critically involved in protective immune reactions classically attributed to T cells. Specifically, antibodies have been documented to protect from many primary viral and parasitic infections and to be indispensable for the control of latent viral infections. Current vaccine strategies should take into account this pivotal role of antibodies.
引用
收藏
页码:332 / 339
页数:8
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