Adverse effects of nutritional inadequacy and excess: a hormetic model

被引：40
作者：
Hayes, Daniel P. [1 ]
机构：
[1] New York City Dept Hlth & Mental Hyg, New York, NY 10007 USA
来源：
AMERICAN JOURNAL OF CLINICAL NUTRITION | 2008年 / 88卷 / 02期
关键词：
D O I：
10.1093/ajcn/88.2.578S
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
I address and explain the increased risk of adverse effects from nutrients by using the paradigm of hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities. To provide necessary background, I categorize, depict, discuss, and contrast hormetic and other dose-response relations. I review some of the different hormetic mechanisms that others have proposed. I then use the hormetic paradigm to explain adverse effects from essential nutrients, including vitamin D. The hormesis paradigm could be useful to nutritional scientists in their consideration of nutritional adverse effects.
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收藏
页码：578S / 581S
页数：4
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