Suppression IL-12 in children with severe malarial anemia occurs through hemozoin-induced overproduction of IL-10

被引：0
|
作者：
Keller, Christopher C. [1 ]
Ong'echa, John Michael [2 ]
Ouma, Collins [2 ]
Otieno, Richard O. [3 ]
Were, Tom [4 ]
Vulule, John M. [5 ]
Perkins, Douglas J. [1 ]
机构：
[1] Univ Pittsburgh, Dept Infect Dis & Microbiol, Grad Sch Publ Hlth, Pittsburgh, PA USA
[2] Univ Pittsburgh, KEMRI Lab Parasit & Viral Dis, Kenya Med Res Inst, Ctr Vector Biol & Control Res, Kisumu, Kenya
[3] Maseno Univ, Dept Zool, Kisumu, Kenya
[4] Kenyatta Univ, Sch Hlth Sci, Dept Pathol, Nairobi, Kenya
[5] Ctr Vector Biol & Control Res, Kisumu, Kenya
来源：
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2005年 / 73卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
394
引用
收藏
页码：131 / 131
页数：1
相关论文
共 50 条
  • [41] Relationship between plasma interleukin-12 (IL-12) and IL-18 levels and severe malarial anemia in an area of holoendemicity in western Kenya
    Chaisavaneeyakorn, S
    Othoro, C
    Shi, YP
    Otieno, J
    Chaiyaroj, SC
    Lal, AA
    Udhayakumar, V
    CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2003, 10 (03) : 362 - 366
  • [42] The Multikinase Inhibitor Sorafenib Reverses the Suppression of IL-12 and Enhancement of IL-10 by PGE2 in Murine Macrophages
    Edwards, Justin P.
    Emens, Leisha
    JOURNAL OF IMMUNOTHERAPY, 2010, 33 (08) : 869 - 869
  • [43] The multikinase inhibitor Sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE2 in murine macrophages
    Edwards, Justin P.
    Emens, Leisha A.
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2010, 10 (10) : 1220 - 1228
  • [44] In vitro production of IFN-r, IL-4, IL-10, IL-12, IL-13 and IgE in asthmatic children
    Hsieh, KH
    Chou, CC
    Chiang, BL
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 97 (01) : 907 - 907
  • [45] Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness
    Fu, Chi-Ling
    Ye, Yi-Ling
    Lee, Yueh-Lun
    Chiang, Bor-Luen
    RESPIRATORY RESEARCH, 2006, 7 (1)
  • [46] Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness
    Chi-Ling Fu
    Yi-Ling Ye
    Yueh-Lun Lee
    Bor-Luen Chiang
    Respiratory Research, 7
  • [47] THE SIGNIFICANCE OF SERUM IL-10 AND IL-12 AS MARKERS OF PROGNOSIS AND RESPONSE TO THERAPY IN CHILDREN WITH SOFT TISSUE SARCOMAS
    Bien, E.
    Krawczyk, M.
    Izycka-Swieszewska, E.
    Trzonkowski, P.
    Kazanowska, B.
    Adamkiewicz-Drozynska, E.
    Balcerska, A.
    PEDIATRIC BLOOD & CANCER, 2013, 60 : 96 - 96
  • [48] Production of IL-2, IL-12, and IL-10 by human blood myeloid dendritic cells
    Hardy, MY
    Kassianos, AJ
    Clark, GJ
    Hart, DNJ
    Radford, KJ
    TISSUE ANTIGENS, 2005, 66 (05): : 437 - 437
  • [49] Seminal Levels of IL-10, IL-12, and IL-17 in Men with Asymptomatic Chlamydia Infection
    Hakimi, Hamid
    Akhondi, Mohammad Mehdi
    Sadeghi, Mohammad Reza
    Chamani, Leila
    Arababadi, Mohammad Kazemi
    Ahmadabadi, Behzad Nasiri
    Hassanshahi, Gholamhossein
    Fathollahi, Mahmoud Sheikh
    INFLAMMATION, 2014, 37 (01) : 122 - 126
  • [50] Production of IL-10 by human natural killer cells stimulated with IL-2 and/or IL-12
    Mehrotra, PT
    Donnelly, RP
    Wong, S
    Kanegane, H
    Geremew, A
    Mostowski, HS
    Furuke, K
    Siegel, JP
    Bloom, ET
    JOURNAL OF IMMUNOLOGY, 1998, 160 (06): : 2637 - 2644
12345