Thrombocytopenia and emperipolesis in a patient with hepatitis A infection

被引:14
作者
Avci, Z
Turul, T
Çatal, F
Olgar, E
Baykan, A
Teksam, Ö
Gürgey, A
机构
[1] Hacettepe Univ, Sch Med, Dept Pediat, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Sch Med, Dept Pediat, Pediat Hematol Unit, TR-06100 Ankara, Turkey
关键词
emperipolesis; hepatitis A virus; thrombocytopenia;
D O I
10.1080/088800102753356211
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Immune thrombocytopenia is a benign, self-limiting disease in children, responding well to treatment and generally associated with viral infections. A 13-year-old girl was admitted to a hospital with the epistaxis and propura after an attack of jaundice 6 weeks before. The diagnosis of hepatitis A virus (HAV)-induced thrombocytopenia was made. Furthermore, erythrophagocytosis by megakaryocytes was demonstrated in the bone marrow of the patient. Although hematologic complications following hepatitis B and C viruses are commonly reported, the association of hepatitis A vir-us and thrombocytopenia has rarely been described.
引用
收藏
页码:67 / 70
页数:4
相关论文
共 17 条
[1]   Idiopathic thrombocytopenic purpura [J].
Bolton-Maggs, PHB .
ARCHIVES OF DISEASE IN CHILDHOOD, 2000, 83 (03) :220-222
[2]   Assessment of UK practice for management of acute childhood idiopathic thrombocytopenic purpura against published guidelines [J].
BoltonMaggs, PHB ;
Moon, I .
LANCET, 1997, 350 (9078) :620-623
[3]   Extrahepatic manifestations associated with hepatitis C virus infection - A prospective multicenter study of 321 patients [J].
Cacoub, P ;
Renou, C ;
Rosenthal, E ;
Cohen, P ;
Loury, I ;
Loustaud-Ratti, V ;
Yamamoto, AM ;
Camproux, AC ;
Hausfater, P ;
Musset, L ;
Veyssier, P ;
Raguin, G ;
Piette, JC .
MEDICINE, 2000, 79 (01) :47-56
[4]   THROMBOCYTOPENIC PURPURA AS A MANIFESTATION OF ACUTE HEPATITIS-A [J].
COHEN, O ;
MEVORACH, D ;
ACKERMAN, Z ;
OREN, R .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 1993, 17 (02) :166-167
[5]  
DJALDETTI M, 1982, J SUBMICR CYTOL PATH, V14, P407
[6]   Thrombotic and thrombocytopenic complications secondary to hepatitis A infection in children [J].
Ertem, D ;
Acar, Y ;
Arat, C ;
Pehlivanoglu, E .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 1999, 94 (12) :3653-3655
[7]   High prevalence of anticardiolipin antibodies in hepatitis C virus infection: lack of effects on thrombocytopenia and thrombotic complications [J].
Harada, M ;
Fujisawa, Y ;
Sakisaka, S ;
Kawaguchi, T ;
Taniguchi, E ;
Sakamoto, M ;
Sumie, S ;
Sasatomi, K ;
Koga, H ;
Torimura, T ;
Ueno, T ;
Gondo, K ;
Yoshida, H ;
Tanikawa, K ;
Sata, M .
JOURNAL OF GASTROENTEROLOGY, 2000, 35 (04) :272-277
[8]   IMMUNE THROMBOCYTOPENIC PURPURA ASSOCIATED WITH HEPATITIS-A [J].
IBARRA, H ;
ZAPATA, C ;
INOSTROZA, J ;
MEZZANO, S ;
RIEDEMANN, S .
BLUT, 1986, 52 (06) :371-375
[9]   THROMBOCYTOPENIC PURPURA DURING THE INCUBATION OF HEPATITIS-B [J].
KORMAN, SH .
ACTA PAEDIATRICA SCANDINAVICA, 1991, 80 (10) :975-976
[10]  
Kyoda K, 1998, AM J GASTROENTEROL, V93, P1187