VIROLOGY Bird flu in mammals

被引:11
作者
Yen, Hui-Ling [1 ,2 ,3 ]
Peiris, Joseph Sriyal Malik [1 ,2 ,3 ]
机构
[1] Univ Hong Kong, Sch Publ Hlth, Pokfulam, Hong Kong, Peoples R China
[2] Univ Hong Kong, Influenza Res Ctr, LKS Fac Med, Pokfulam, Hong Kong, Peoples R China
[3] HKU Pasteur Res Ctr, Pokfulam, Hong Kong, Peoples R China
关键词
INFLUENZA-A VIRUS; H5N1; VIRUSES; AVIAN H5N1; RECEPTOR SPECIFICITY; TRANSMISSION; HEMAGGLUTININ; MUTATIONS; BINDING; H1N1;
D O I
10.1038/nature11192
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
An engineered influenza virus based on a haemagglutinin protein from H5N1 avian influenza, with just four mutations, can be transmitted between ferrets, emphasizing the potential for a human pandemic to emerge from birds. See Letter p.420
引用
收藏
页码:332 / 333
页数:2
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