SECTOR LASER PHOTOCOAGULATION FOR THE PREVENTION OF MACULAR EDEMA AFTER PLAQUE RADIOTHERAPY FOR UVEAL MELANOMA A Pilot Study

被引:27
|
作者
Materin, Miguel A. [1 ,2 ]
Bianciotto, Carlos G. [2 ]
Wu, Chengqing [3 ]
Shields, Carol L. [2 ]
机构
[1] Yale Univ, Sch Med, Dept Ophthalmol, Ocular Oncol Sect, New Haven, CT 06443 USA
[2] Thomas Jefferson Univ, Wills Eye Inst, Ocular Oncol Serv, Philadelphia, PA 19107 USA
[3] Yale Univ, Sch Med, Dept Publ Hlth, New Haven, CT 06443 USA
来源
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2012年 / 32卷 / 08期
关键词
eye; uvea; melanoma; plaque radiotherapy; macular edema; sector laser; sector panretinal photocoagulation; INTRAVITREAL TRIAMCINOLONE ACETONIDE; RADIATION MACULOPATHY; CHOROIDAL MELANOMA; DIABETIC-RETINOPATHY; CONSECUTIVE PATIENTS; TUMOR-CONTROL; COMPLICATIONS; BRACHYTHERAPY; PAPILLOPATHY; IRRADIATION;
D O I
10.1097/IAE.0b013e3182437e70
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Objective: To investigate the role of sector laser photocoagulation for prevention of macular edema after plaque radiotherapy for uveal melanoma. Methods: Noncomparative, pilot interventional case series. The main outcome measure was optical coherence tomography-evident macular edema. Results: A total of 29 patients had sector laser photocoagulation (sector panretinal photocoagulation) and sub-Tenon triamcinolone injection. The median tumor thickness and base was 3.3 mm and 10.0 mm. The median radiation dose and rate to the macula was 2,944 cGy and 31.0 cGy/hour. At the 12-month and 24-months follow-up, cystoid macular edema was found in 17% and 24% of the sector panretinal photocoagulation group. There were no major side effects registered. Conclusion: Sector panretinal photocoagulation in combination with sub-Tenon triamcinolone appears to show potential as a safe and beneficial intervention for the prevention of macular edema after plaque radiotherapy for uveal melanoma in this series. RETINA 32:1601-1607, 2012
引用
收藏
页码:1601 / 1607
页数:7
相关论文
共 40 条
  • [31] Aqueous flare measured with the laser-flare-meter in patients with diabetic macular edema before and after grid photocoagulation
    Wiedemann, R
    Walter, A
    Wiedemann, P
    KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 1998, 212 (01) : 32 - 36
  • [32] Radiation Macular Edema after Ru-106 Plaque Brachytherapy for Choroidal Melanoma Resolved by an Intravitreal Dexamethasone 0.7-mg Implant
    Russo, Andrea
    Avitabile, Teresio
    Uva, Maurizio
    Faro, Salvatore
    Franco, Livio
    Sanfilippo, Marisa
    Gulisano, Seby
    Toro, Mario
    De Grande, Vittorio
    Rametta, Stefania
    Foti, Laura
    Longo, Antonio
    Reibaldi, Michele
    CASE REPORTS IN OPHTHALMOLOGY, 2012, 3 (01): : 71 - 76
  • [33] Indocyanine-green-guided targeted laser photocoagulation of capillary macroaneurysms in macular oedema: a pilot study
    Paques, Michel
    Philippakis, Elise
    Bonnet, Clemence
    Falah, Sabrina
    Ayello-Scheer, Sarah
    Zwillinger, Stephanie
    Girmens, Jean-Francois
    Dupas, Benedicte
    BRITISH JOURNAL OF OPHTHALMOLOGY, 2017, 101 (02) : 170 - 174
  • [34] RETINAL MICROVASCULAR CHANGES IN UVEAL MELANOMA FOLLOWING CONBERCEPT INJECTION AFTER PLAQUE RADIOTHERAPY AS DETECTED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
    Yang, Jing Yan
    Wang, Qian
    Chen, Meng Xi
    Yan, Yan Ni
    Zhou, Wen Jia
    Liu, Yue Ming
    Wei, Wen Bin
    RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2021, 41 (12): : 2605 - 2611
  • [35] Circulating melanoma cells in peripheral blood of patients with uveal melanoma before and after different therapies and association with prognostic parameters: a pilot study
    Suesskind, Daniela
    Ulmer, Anja
    Schiebel, Ursel
    Fierlbeck, Gerhard
    Spitzer, Bernhard
    Spitzer, Martin S.
    Bartz-Schmidt, Karl U.
    Grisanti, Salvatore
    ACTA OPHTHALMOLOGICA, 2011, 89 (01) : 17 - 24
  • [36] Long-term effect of early intervention with single intravitreal injection of bevacizumab followed by panretinal and macular grid photocoagulation in central retinal vein occlusion (CRVO) with macular edema: A pilot study
    N J Shah
    U N Shah
    Eye, 2011, 25 : 239 - 244
  • [37] Long-term effect of early intervention with single intravitreal injection of bevacizumab followed by panretinal and macular grid photocoagulation in central retinal vein occlusion (CRVO) with macular edema: A pilot study
    Shah, N. J.
    Shah, U. N.
    EYE, 2011, 25 (02) : 239 - 244
  • [38] A quantitative in vivo study of retinal thickness before and after laser treatment for macular edema due to retinal vein occlusion
    De Geronimo, F
    Glacet-Bernard, A
    Coscas, G
    Soubrane, G
    EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2001, 11 (02) : 145 - 149
  • [39] Novel Triamcinolone Acetonide-Loaded Liposomes Topical Formulation for the Treatment of Cystoid Macular Edema After Cataract Surgery: A Pilot Study
    Gonzalez-De la Rosa, Alejandro
    Navarro-Partida, Jose
    Carlos Altamirano-Vallejo, Juan
    Gabriela Hernandez-Gamez, Ada
    Javier Garcia-Banuelos, Jesus
    Armendariz-Borunda, Juan
    Santos, Arturo
    JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2019, 35 (02) : 106 - 115
  • [40] Photocoagulation or sham laser in addition to conventional anti-VEGF therapy in macular edema associated with TelCaps due to diabetic macular edema or retinal vein occlusion (TalaDME): a study protocol for a multicentric, French, two-group, non-commercial, active-control, observer-masked, non-inferiority, randomized controlled clinical trial
    Dupas, Benedicte
    Castro-Farias, Daniela
    Girmens, Jean-Francois
    Eginay, Ali
    Couturier, Aude
    Villeroy, Frederic
    Delyfer, Marie-Noelle
    Creuzot-Garcher, Catherine
    Giocanti-Auregan, Audrey
    Beral, Laurence
    Arndt, Carl
    Mesnard, Charles
    Vicaut, Eric
    Chaumet-Riffaud, Philippe
    Durand-Zaleski, Isabelle
    Paques, Michel
    TRIALS, 2024, 25 (01)