Research on Modular Construction of Gene Regulatory Network

Gene regulatory network is a large number of genes regulated by transcriptional factors and translated into protein complex information so as to realize the biological function, is an important part of people's understanding of biological processes and gene function. In order to understand the regulatory mechanism of gene regulatory networks, the network topology and its organization is one of the most important research contents. It can not only describe the local characteristics of the network, but also can reveal the construction method of the control network. The control network can be divided into 4 layers: control elements, Motif, modules and the whole network. At present, more and more people have recognized the hierarchy. Motif and two key module is discussed in this article are compared and analyzed in recent years on many aspects of the research content of network organization structure, expounds the biological significance of various research results and conclusion have, and pointed out the existing problems. On this basis, the paper also puts forward the possible research direction for these problems, and looks forward to the prospect of modular organization of gene regulatory network.