Flaxseed and Human Health: Reviewing Benefits and Adverse Effects

被引:63
作者
Cardoso Carraro, Julia Cristina [1 ]
de Souza Dantas, Maria Ines [1 ]
Rocha Espeschit, Ana Cristina [1 ]
Duarte Martino, Hercia Stampini [1 ]
Rocha Ribeiro, Sonia Machado [1 ]
机构
[1] Univ Fed Vicosa, Dept Nutr & Hlth, BR-36570000 Vicosa, MG, Brazil
关键词
disease prevention; flaxseed; health; phytochemicals; ALPHA-LINOLENIC-ACID; DIETARY-FAT RESTRICTION; BREAST-TUMOR GROWTH; SECOISOLARICIRESINOL DIGLUCOSIDE; METABOLIC SYNDROME; LINUM-USITATISSIMUM; OIL SUPPLEMENTATION; PROSTATE-CANCER; LIGNAN COMPLEX; DOUBLE-BLIND;
D O I
10.1080/87559129.2011.595025
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Consumption of flaxseed has been increased due to its possible functional properties in health. However, its chronic consumption may offer risks considering the effects of lignans in men and in pregnant women, as well as the existence of other phytochemicals and toxic factors with adverse health effects in the seed. The present review focuses on the growing body of evidence on the potential health benefits of flaxseed in humans, with supporting evidence from human and animal studies. It also raises questions that provide input for future research on the effects of flaxseed ingestion in terms of nutrient bioavailability and human fertility.
引用
收藏
页码:203 / 230
页数:28
相关论文
共 139 条
  • [41] The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis
    Fuchs, Dagmar
    Piller, Regina
    Linseisen, Jakob
    Daniel, Hannelore
    Wenze, Uwe
    [J]. PROTEOMICS, 2007, 7 (18) : 3278 - 3288
  • [42] Flaxseed lignan attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice
    Fukumitsu, S.
    Aida, K.
    Ueno, N.
    Ozawa, S.
    Takahashi, Y.
    Kobori, M.
    [J]. BRITISH JOURNAL OF NUTRITION, 2008, 100 (03) : 669 - 676
  • [43] Neonatal estrogen exposure of male rats alters reproductive functions at adulthood
    Goyal, HO
    Robateau, A
    Braden, TD
    Williams, CS
    Srivastava, KK
    Ali, K
    [J]. BIOLOGY OF REPRODUCTION, 2003, 68 (06) : 2081 - 2091
  • [44] Pressure and temperature combination for inactivation of soymilk trypsin inhibitors
    Guerrero-Beltran, Jose A.
    Estrada-Giron, Yokiushirdhilgilmara
    Swanson, Barry G.
    Barbosa-Canovas, Gustavo V.
    [J]. FOOD CHEMISTRY, 2009, 116 (03) : 676 - 679
  • [45] Guseva D. A., 2010, Voprosy Pitaniya, V79, P13
  • [46] Haliga Raluca, 2009, Rev Med Chir Soc Med Nat Iasi, V113, P1200
  • [47] Haliga Raluca, 2007, Rev Med Chir Soc Med Nat Iasi, V111, P472
  • [48] The effect of a lignan complex isolated from flaxseed on inflammation markers in healthy postmenopausal women
    Hallund, J.
    Tetens, I.
    Bugel, S.
    Tholstrup, T.
    Bruun, J. M.
    [J]. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2008, 18 (07) : 497 - 502
  • [49] A lignan complex isolated from flaxseed does not affect plasma lipid concentrations or antioxidant capacity in healthy postmenopausal women
    Hallund, J
    Ravn-Haren, G
    Bügel, S
    Tholstrup, T
    Tetens, I
    [J]. JOURNAL OF NUTRITION, 2006, 136 (01) : 112 - 116
  • [50] ORAL ALPHA-TOCOPHEROL SUPPLEMENTS DECREASE PLASMA GAMMA-TOCOPHEROL LEVELS IN HUMANS
    HANDELMAN, GJ
    MACHLIN, LJ
    FITCH, K
    WEITER, JJ
    DRATZ, EA
    [J]. JOURNAL OF NUTRITION, 1985, 115 (06) : 807 - 813