Treatment of amitriptyline poisoning with ovine antibody to tricyclic antidepressants

被引：14

作者：

Heard, K ^{[1
]}

O'Malley, GF

Dart, RC

机构：

[1] Denver Hlth Author, Rocky Mt Poison & Drug Ctr, Denver, CO 80220 USA

[2] Univ Colorado, Hlth Sci Ctr, Emergency Med Res Ctr, Boulder, CO 80309 USA

来源：

LANCET | 1999年 / 354卷 / 9190期

关键词：

D O I：

10.1016/S0140-6736(99)03358-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report clinical improvement with the use of an ovine antibody (Fab fragment) to tricyclic antidepressants for the treatment of toxic effects of amitriptyline on the central nervous system and heart in a 48-year-old man.

引用

页码：1614 / 1615

页数：2

共 5 条

[1] THE TOXICITY OF DRUGS USED FOR SUICIDE [J].

CROME, P .

ACTA PSYCHIATRICA SCANDINAVICA, 1993, 87 :33-37

[2] Ovine desipramine antibody fragments reverse desipramine cardiovascular toxicity in the rat [J].

Dart, RC ;

Sidki, A ;

Sullivan, JB ;

Egen, NB ;

Garcia, RA .

ANNALS OF EMERGENCY MEDICINE, 1996, 27 (03) :309-315

[3]

SERAFIMOVSKI N, 1975, ACTA ANAESTH SCAND, P55

[4] ACUTE SELF-POISONING WITH TRICYCLIC ANTIDEPRESSANTS IN 295 CONSECUTIVE PATIENTS TREATED IN AN ICU [J].

STROM, J ;

MADSEN, PS ;

NIELSEN, NN ;

SORENSEN, MB .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1984, 28 (06) :666-670

[5]

THORSTRAND C, 1976, ACTA MED SCAND, V199, P337

← 1 →