Synthesis, characterization, swelling and drug release behavior of semi-interpenetrating network hydrogels of sodium alginate and polyacrylamide

被引：225

作者：

Samanta, Himadri Sekhar ^{[1
]}

Ray, Samit Kumar ^{[1
]}

机构：

[1] Univ Calcutta 92, Dept Polymer Sci & Technol, Kolkata 700009, India

来源：

CARBOHYDRATE POLYMERS | 2014年 / 99卷

关键词：

Sodium alginate; Acrylamide; Semi-IPN hydrgels; Characterization; Drug release; SUPERABSORBENT HYDROGELS; SUPERPOROUS HYDROGELS; POLYMER NETWORKS; REMOVAL; DYES; PARAMETERS; DELIVERY; METHACRYLATE); ACRYLATE); COPOLYMER;

D O I：

10.1016/j.carbpol.2013.09.004

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Several semi interpenetrating network (SIPN) type hydrogels were synthesized by in-situ free radical crosslink copolymerization of acrylamide and crosslinker N,N'-methylene bisacrylamide (MBA) in aqueous solution of sodium alginate (SA). These SIPN hydrogels were characterized by FTIR, NMR SEM, DTA-TGA, XRD, PZC and also by swelling characteristics and network parameters. Adsorption (loading) and release of acetaminophen drug were studied with these hydrogels. Solution pH, crosslinker concentration and monomer to SA weight ratio of the hydrogels were found to have a strong effect on adsorption and in vitro release profile of the drug from the gel matrix. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：666 / 678

页数：13

共 50 条

[21] Swelling behavior of semi-interpenetrating polymer network hydrogels composed of poly(vinyl alcohol) and poly(acrylamide-co-Sodium methacrylate)
Mohan, YM
Murthy, PSK
Sreeramulu, J
Raju, KM
JOURNAL OF APPLIED POLYMER SCIENCE, 2005, 98 (01) : 302 - 314
[22] Adsorption Kinetics/Thermodynamic Behavior and Adsorption/Desorption Mechanism of Crystal Violet by Semi-interpenetrating Sodium Alginate/Polyacrylamide Hydrogel
Li Zhigang
Zhang Yixuan
Zhang Qingsong
Ma Youwei
Hu Tao
Bai Haihui
Liu Pengfei
Wang Ke
Zhang Xiaoyong
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2017, 38 (11): : 2118 - 2127
[23] Synthesis and characteristics of semi-interpenetrating polymer network hydrogels of chitosan and polyaniline
Shin, SR
Park, SJ
Yoon, SG
Lee, CK
Kim, IY
Kim, SI
Kim, SJ
SMART STRUCTURES AND MATERIALS 2004: ELECTROACTIVE POLYMER ACTUATORS AND DEVICES (EAPAD), 2004, 5385 : 490 - 499
[24] Preparation and characterization of pH-sensitive semi-interpenetrating network hybrid hydrogels with sodium humate and kaolin
Yilmaz, Elif
Kaya, Gulcihan Guzel
Deveci, Huseyin
APPLIED CLAY SCIENCE, 2018, 162 : 311 - 316
[25] Synthesis and swelling characteristics of semi-interpenetrating polymer network hydrogels composed of poly(acrylamide) and poly(γ-glutamic acid)
Rodríguez, DE
Romero-Garcia, J
Ramírez-Vargas, E
Ledezma-Pérez, AS
Arías-Marín, E
MATERIALS LETTERS, 2006, 60 (11) : 1390 - 1393
[26] Novel poly(HEMA-co-METAC)/alginate semi-interpenetrating hydrogels for biomedical applications: Synthesis and characterization
La Gatta, Annalisa
Schiraldi, Chiara
Esposito, Annaclaudia
D'Agostino, Antonella
De Rosa, Alfredo
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2009, 90A (01) : 292 - 302
[27] Characterization and drug release kinetics of polyacrylamide/sodium alginate blend hydrogels synthesized by gamma irradiation
Horia M. Nizam El-Din
Abdel Wahab M. El-Naggar
Faten I. Abu-El Fadle
Polymer Bulletin, 2024, 81 : 6149 - 6171
[28] Characterization and drug release kinetics of polyacrylamide/sodium alginate blend hydrogels synthesized by gamma irradiation
Nizam El-Din, Horia M.
El-Naggar, Abdel Wahab M.
Abu-El Fadle, Faten I.
POLYMER BULLETIN, 2024, 81 (07) : 6149 - 6171
[29] Silk Semi-Interpenetrating Network Hydrogels for Biomedical Applications
Thananukul, Kamonchanok
Jarruwale, Pakkamon
Suttenun, Nuchada
Thordason, Pall
Punyamoonwongsa, Patchara
MACROMOLECULAR SYMPOSIA, 2015, 354 (01) : 251 - 257
[30] Synthesis and characterization of antibacterial semi-interpenetrating carboxymethyl chitosan/poly (acrylonitrile) hydrogels
Riham R. Mohamed
Rania S. Seoudi
Magdy. W. Sabaa
Cellulose, 2012, 19 : 947 - 958

← 1 2 3 4 5 →