18F-FDG PET/CT in Labrune Syndrome

被引：1
作者：
Cuzzocrea, Marco [1 ]
Florimonte, Luigia [1 ]
Scola, Elisa [2 ]
Benti, Riccardo [1 ]
Castellani, Massimo [1 ]
机构：
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Nucl Med, Via Francesco Sforza 35, I-20122 Milan, Italy
[2] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Neuroradiol, Milan, Italy
来源：
CLINICAL NUCLEAR MEDICINE | 2020年 / 45卷 / 10期
关键词：
brain PET/CT; FDG; Labrune syndrome; leukoencephalopathy; MRI; CEREBRAL CALCIFICATIONS; BRAIN CALCIFICATIONS; LEUKOENCEPHALOPATHY; CYSTS; MUTATIONS; MICROANGIOPATHY;
D O I：
10.1097/RLU.0000000000003199
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 69-year-old woman presented with cognitive impairment related to attentive, executive, and mnemonic functions; progressive worsening of walking, speaking, writing, and reading ability; and double sphincter incontinence. Leukoencephalopathy, cystic lesions, and calcifications, suspected for Labrune syndrome, were observed at MRI and CT brain images. Generalized wave abnormalities were also visible at electroencephalogram. Functional brain imaging performed with F-18-FDG PET/CT demonstrated a decreased glucose metabolism in impaired brain regions, in accordance with MRI findings. Genetic testing confirmed a mutation of SNORD118.
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收藏
页码：E439 / E440
页数：2
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