In Vitro and In Vivo Experimental Models as Tools to Investigate the Efficacy of Antineoplastic Drugs on Urinary Bladder Cancer

被引：1

作者：

Arantes-Rodrigues, Regina ^{[1
]}

Colaco, Aura ^{[1
]}

Pinto-Leite, Rosario ^{[2
]}

Oliveira, Paula A. ^{[1
]}

机构：

[1] Univ Tras Os Montes & Alto Douro, Dept Vet Sci, CECAV, P-5001801 Vila Real, Portugal

[2] Hosp Ctr Tras Os Montes & Alto Douro, Cytogenet Lab, Genet Serv, Vila Real, Portugal

来源：

ANTICANCER RESEARCH | 2013年 / 33卷 / 04期

关键词：

Urinary bladder cancer; in vitro models; in vivo models; antineoplastic drugs; review; TRANSITIONAL-CELL-CARCINOMA; BACILLUS-CALMETTE-GUERIN; SELECTIVE CYCLOOXYGENASE-2 INHIBITOR; PHASE-II TRIAL; TYPE-1 RECEPTOR ANTAGONIST; GROWTH-FACTOR-RECEPTOR; INDUCED APOPTOSIS; N-BUTYL-N-(4-HYDROXYBUTYL) NITROSAMINE; UROTHELIAL CARCINOMA; TUMOR-GROWTH;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity.

引用

页码：1273 / 1296

页数：24

共 228 条

[1] Tumor markers of bladder cancer: the schistosomal bladder tumors versus non-schistosomal bladder tumors [J].

Abdulamir, Ahmed S. ;

Hafidh, Rand R. ;

kadhim, Haider S. ;

Abubakar, Fatimah .

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2009, 28

[2] Divergent effects of taurolidine as potential anti-neoplastic agent: Inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo [J].

Abramjuk, Claudia ;

Bueschges, Michael ;

Schnorr, Joerg ;

Jung, Klaus ;

Staack, Andrea ;

Lein, Michael .

ONCOLOGY REPORTS, 2009, 22 (02) :409-414

[3] Randomized Phase III Trial on Gemcitabine Versus Mytomicin in Recurrent Superficial Bladder Cancer: Evaluation of Efficacy and Tolerance [J].

Addeo, Raffaele ;

Caraglia, Michele ;

Bellini, Sergio ;

Abbruzzese, Alberto ;

Vincenzi, Bruno ;

Montella, Liliana ;

Miragliuolo, Antonio ;

Guarrasi, Rosario ;

Lanna, Michele ;

Cennamo, Gregorio ;

Faiola, Vincenzo ;

Del Prete, Salvatore .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (04) :543-548

[4] In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines [J].

Adhim, Z. ;

Matsuoka, T. ;

Bito, T. ;

Shigemura, K. ;

Lee, K-M ;

Kawabata, M. ;

Fujisawa, M. ;

Nibu, K. ;

Shirakawa, T. .

BRITISH JOURNAL OF CANCER, 2011, 105 (03) :393-402

[5] A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro [J].

Andrews, Peter ;

Zhao, Xu ;

Allen, Jeffrey ;

Li, Fengmin ;

Chang, Melissa .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2008, 61 (02) :203-214

[6]

[Anonymous], 2004, WHO CLASSIFICATION T

[7] Meloxicam synergistically enhances the in vitro effects of sunitinib malate on bladder-cancer cells [J].

Arantes-Rodrigues, Regina ;

Pinto-Leite, Rosario ;

Fidalgo-Goncalves, Lio ;

Gaivao, Isabel ;

Colaco, Aura ;

Oliveira, Paula ;

Santos, Lucio .

JOURNAL OF APPLIED BIOMEDICINE, 2013, 11 (02) :79-92

[8] Experimental rat bladder urothelial cell carcinoma models [J].

Arentsen, Harm C. ;

Hendricksen, Kees ;

Oosterwijk, Egbert ;

Witjes, J. Alfred .

WORLD JOURNAL OF UROLOGY, 2009, 27 (03) :313-317

[9] Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment [J].

Azuma, H ;

Takahara, S ;

Horie, S ;

Muto, S ;

Otsuki, Y ;

Katsuoka, Y .

JOURNAL OF UROLOGY, 2003, 169 (06) :2372-2377

[10] EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder [J].

Babjuk, Marko ;

Oosterlinck, Willem ;

Sylvester, Richard ;

Kaasinen, Eero ;

Boehle, Andreas ;

Palou-Redorta, Juan .

EUROPEAN UROLOGY, 2008, 54 (02) :303-314

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